Evidence map›Paper›PMID 33925935›Full record

ArticleInternational journal of molecular sciences2021

Aggregation and Its Influence on the Bioactivities of a Novel Antimicrobial Peptide, Temporin-PF, and Its Analogues.

Yu Zai, Xinping Xi, Zhuming Ye, Chengbang Ma, Mei Zhou, Xiaoling Chen, Shirley W I Siu, Tianbao Chen, Lei Wang, Hang Fai Kwok

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. The Probiotic Effects ofInternational journal of microbiology · 2026
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  14. Review
  15. Deciphering the Molecular Mechanism of Escin against Neuropathic Pain: A Network Pharmacology Study.Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
  16. Article
  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Yu ZaiInstitute of Translational Medicine, Faculty of Health Sciences, University of Macau, Avenida da Univesidade, Taipa, Macau, China.
Xinping XiSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Zhuming YeSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Chengbang MaSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Mei ZhouSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0003-2576-0252
Xiaoling ChenSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Shirley W I SiuDepartment of Computer and Information Science, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau, China.
Tianbao ChenSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0001-8011-9260
Lei WangSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.ORCID 0000-0002-8811-8489
Hang Fai KwokInstitute of Translational Medicine, Faculty of Health Sciences, University of Macau, Avenida da Univesidade, Taipa, Macau, China.ORCID 0000-0002-6349-4517
Queen's University Belfast · GBUniversity of Macau · MO

Funding

Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Fundo para o Desenvolvimento das Ciências e da Tecnologia 0055/2019/A1Fundo para o Desenvolvimento das Ciências e da Tecnologia 019/2017/A1NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

Temporin is an antimicrobial peptide (AMP) family discovered in the skin secretion of ranid frog that has become a promising alternative for conventional antibiotic therapy. Herein, a novel temporin peptide, Temporin-PF (TPF), was successfully identified from

Indexed as

Amino Acid SequenceAmphibian ProteinsAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBodily SecretionsHydrogen-Ion ConcentrationHydrophobic and Hydrophilic InteractionsMicrobial Sensitivity TestsPore Forming Cytotoxic ProteinsProtein AggregatesRanidaeSalt StressSkinAmphibian ProteinsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesPore Forming Cytotoxic ProteinsProtein Aggregatestemporinantimicrobial activityMD simulationpeptide aggregationtemporin

Identifiers

PMID33925935
PMCPMC8123395
OpenAlexW3159338755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.