Evidence map›Paper›PMID 33925933›Full record

ArticleInternational journal of molecular sciences2021

Overexpression of

Tetyana Chumak, Diana Tothova, Iva Filova, Zbynek Bures, Jiri Popelar, Gabriela Pavlinkova, Josef Syka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tetyana ChumakInstitute of Experimental Medicine CAS, Vídenska 1083, 14220 Prague, Czech Republic.
Diana TothovaInstitute of Experimental Medicine CAS, Vídenska 1083, 14220 Prague, Czech Republic.
Iva FilovaInstitute of Biotechnology CAS, 25250 Vestec, Czech Republic.
Zbynek BuresInstitute of Experimental Medicine CAS, Vídenska 1083, 14220 Prague, Czech Republic.
Jiri PopelarInstitute of Experimental Medicine CAS, Vídenska 1083, 14220 Prague, Czech Republic.
Gabriela PavlinkovaInstitute of Biotechnology CAS, 25250 Vestec, Czech Republic.ORCID 0000-0002-5689-6577
Josef SykaInstitute of Experimental Medicine CAS, Vídenska 1083, 14220 Prague, Czech Republic.
Czech Academy of Sciences, Institute of Experimental Medicine · CZCzech Academy of Sciences, Institute of Biotechnology · CZ

Funding

Akademie Věd České Republiky 86652036Grantová Agentura České Republiky 20-06927S
6 · The paper itself

Abstract

The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (

Indexed as

AnimalsAuditory PerceptionAuditory ThresholdBrainEvoked Potentials, Auditory, Brain StemFemaleGene ExpressionHearingHumansInferior ColliculiLIM-Homeodomain ProteinsMaleMiceMice, TransgenicNeuronsPAX2 Transcription Factorinsulin gene enhancer binding protein Isl-1LIM-Homeodomain ProteinsPAX2 protein, humanPax2 protein, mousePAX2 Transcription FactorTranscription Factorsauditory systeminferior colliculusinhibitionsound processingtranscription factor ISL1

Identifiers

PMID33925933
PMCPMC8123449
OpenAlexW3157908277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.