Evidence map›Paper›PMID 33925878›Full record

ArticlePlants (Basel, Switzerland)2021

Argonaute 2 Controls Antiviral Activity against Sweet Potato Mild Mottle Virus in

Erzsébet Kenesi, Juan-Jose Lopez-Moya, László Orosz, József Burgyán, Lóránt Lakatos

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Plant-made pharmaceuticals.Plant biotechnology (Tokyo, Japan) · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Erzsébet KenesiBiological Research Center Szeged, Institute of Plant Biology, Photo- and Chronobiology Group Eötvös Loránd Research Network (ELKH), H-6726 Szeged, Hungary.
Juan-Jose Lopez-MoyaCentre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB Bellaterra, 08193 Barcelona, Spain.ORCID 0000-0002-3176-9651
László OroszDepartment of Medical Microbiology and Immunobiology, University of Szeged, H-6720 Szeged, Hungary.
József BurgyánAgricultural Biotechnology Institute, National Agricultural Research and Innovation, H-2100 Gödöllő, Hungary.
Lóránt LakatosBiological Research Center Szeged, Institute of Plant Biology, Photo- and Chronobiology Group Eötvös Loránd Research Network (ELKH), H-6726 Szeged, Hungary.
HUN-REN Szegedi Biológiai Kutatóközpont · HUAgricultural Biotechnology Institute · HUConsejo Superior de Investigaciones Científicas · ESUniversity of Szeged · HU

Funding

Hungarian Ministry of Technology and Innovation GINOP-2.3.2-15-2016-00015, GINOP-2.3.2-15-2016-00032
6 · The paper itself

Abstract

RNA silencing is a sequence specific post-transcriptional mechanism regulating important biological processes including antiviral defense in plants. Argonaute (AGO) proteins, the catalytic subunits of the silencing complexes, are loaded with small RNAs to execute the sequence specific RNA cleavage or translational inhibition. Plants encode several AGO proteins and a few of them, especially AGO1 and AGO2, have been shown to be required for antiviral silencing. Previously, we have shown that the P1 protein of the sweet potato mild mottle virus (SPMMV) suppresses the primary RNA silencing response by inhibiting AGO1. To analyze the role of AGO2 in antiviral defense against the SPMMV, we performed a comparative study using a wild type and ago2

Indexed as

AGO1AGO2RNA silencingsweet potato mild mottle virus

Identifiers

PMID33925878
PMCPMC8145795
OpenAlexW3159773642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.