Evidence map›Paper›PMID 33925873›Full record

ArticleMarine drugs2021

Antitumor Effects of a Sesquiterpene Derivative from Marine Sponge in Human Breast Cancer Cells.

Li-Yuan Bai, Jui-Hsin Su, Chang-Fang Chiu, Wei-Yu Lin, Jing-Lan Hu, Chia-Hsien Feng, Chih-Wen Shu, Jing-Ru Weng

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Li-Yuan BaiDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Jui-Hsin SuNational Museum of Marine Biology and Aquarium, Pingtung 94450, Taiwan.
Chang-Fang ChiuDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Wei-Yu LinDepartment of Pharmacy, Kinmen Hospital, Ministry of Health and Welfare, Kinmen 89142, Taiwan.
Jing-Lan HuDivision of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung 40447, Taiwan.
Chia-Hsien FengDepartment of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chih-Wen ShuInstitute of Biopharmaceutical Sciences, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0002-7774-0002
Jing-Ru WengDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0003-4934-9126
China Medical University · TWNational Sun Yat-sen University · TWKaohsiung Medical University · TWMinistry of Health and Welfare · TWNational Museum of Marine Biology and Aquarium · TW

Funding

China Medical University Hospital DMR-110-016Ministry of Health and Welfare 11075Ministry of Science and Technology, Taiwan MOST 106-2320-B-110-003-MY3; MOST 107-2313-B-110-003-MY3National Health Research Institutes NHRI-109A1-CACO-13202002NSYSU-KMU Joint Research Project NSYSUKMU 110-P002the Ministry of Health and Welfare, China Medical University Hospital Cancer Research Center of Excellence MOHW109-TDU-B-212-010001; MOHW109-TDU-B-212-134026, MOHW110-TDU-B-212-010001
6 · The paper itself

Abstract

In this study, the anti-proliferative effect of ilimaquinone, a sesquiterpene derivative from the marine sponge, in breast cancer cells was investigated. Ilimaquinone inhibited the proliferation of MCF-7 and MDA-MB-231 breast cancer cells with IC

Indexed as

AnimalsAntineoplastic AgentsApoptosisAutophagyBreast NeoplasmsFemaleHumansMCF-7 CellsMembrane Potential, MitochondrialOxidative StressPoriferaQuinonesReactive Oxygen SpeciesSesquiterpenesSignal TransductionS Phase Cell Cycle CheckpointsAntineoplastic AgentsilimaquinoneQuinonesReactive Oxygen SpeciesSesquiterpenesapoptosisautophagybreast cancercell cycle arrestilimaquinonesponge

Identifiers

PMID33925873
PMCPMC8144972
OpenAlexW3159898980

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.