Evidence map›Paper›PMID 33925860›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Drug Delivery Approaches for Managing Overactive Bladder (OAB): A Systematic Review.

Zara Khizer, Amina Sadia, Raman Sharma, Samia Farhaj, Jorabar Singh Nirwan, Pratibha G Kakadia, Talib Hussain, Abid Mehmood Yousaf, Yasser Shahzad, Barbara R Conway and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Overactive bladder syndrome in nulliparous women.Journal of the Chinese Medical Association : JCMA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Zara KhizerDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Amina SadiaDistrict Headquarter Hospital, Sahiwal 57000, Pakistan.
Raman SharmaParkside Medical Practice, Horton Park Health Centre, Bradford BD7 3EG, UK.ORCID 0000-0002-9591-4627
Samia FarhajDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Jorabar Singh NirwanDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.
Pratibha G KakadiaBehavioral & Social Science, Integrated Behavioral Health Research Institute, San Gabriel, CA 91775, USA.ORCID 0000-0001-6953-8552
Talib HussainDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore 45550, Pakistan.
Abid Mehmood YousafDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore 45550, Pakistan.ORCID 0000-0001-7866-9474
Yasser ShahzadDepartment of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore 45550, Pakistan.
Barbara R ConwayDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.ORCID 0000-0001-5570-3318
Muhammad Usman GhoriDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK.ORCID 0000-0003-1884-6648
University of Huddersfield · GBCOMSATS University Islamabad · PKPakistan Army · PKParkside Hospital · GB

Funding

University of Huddersfield PHM112
6 · The paper itself

Abstract

Overactive bladder syndrome (OAB) is characterised by urgency symptoms, with or without urgency incontinence, usually with frequency and nocturia and severely affects the quality of life. This systematic review evaluates the various drug delivery strategies used in practice to manage OAB. Advanced drug delivery strategies alongside traditional strategies were comprehensively analysed and comparatively evaluated. The present review was conducted according to the preferred reporting items for systematic reviews and meta-analyses guidelines. A total of 24 studies reporting the development of novel formulations for the treatment of OAB were considered eligible and were further categorised according to the route of drug administration. The review found that various drug delivery routes (transdermal, intravesicular, oral, vaginal and intramuscular) are used for the administration of drugs for managing OAB, however, the outcomes illustrated the marked potential of transdermal drug delivery route. The findings of the current review are expected to be helpful for pharmaceutical scientists to better comprehend the existing literature and challenges and is anticipated to provide a basis for designing and fabricating novel drug delivery systems to manage OAB.

Indexed as

drug deliveryoral drug deliveryoveractive bladderpharmacotherapysystematic reviewtransdermal drug delivery

Identifiers

PMID33925860
PMCPMC8146593
OpenAlexW3158557014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.