Evidence map›Paper›PMID 33925843›Full record

ArticleSensors (Basel, Switzerland)2021

Towards a Fully Automated Scanning Probe Microscope for Biomedical Applications.

Witold K Szeremeta, Robert L Harniman, Charlotte R Bermingham, Massimo Antognozzi

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Witold K SzeremetaSchool of Physics, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, UK.ORCID 0000-0001-5932-6126
Robert L HarnimanSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Charlotte R BerminghamSchool of Physics, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, UK.
Massimo AntognozziSchool of Physics, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, UK.ORCID 0000-0001-5396-0564
University of Bristol · GB

Funding

Engineering and Physical Sciences Research Council EP/N509619/1
6 · The paper itself

Abstract

The increase in capabilities of Scanning Probe Microscopy (SPM) has resulted in a parallel increase in complexity that limits the use of this technique outside of specialised research laboratories. SPM automation could substantially expand its application domain, improve reproducibility and increase throughput. Here, we present a bottom-up design in which the combination of positioning stages, orientation, and detection of the probe produces an SPM design compatible with full automation. The resulting probe microscope achieves sub-femtonewton force sensitivity whilst preserving low mechanical drift (2.0±0.2 nm/min in-plane and 1.0±0.1 nm/min vertically). The additional integration of total internal reflection microscopy, and the straightforward operations in liquid, make this instrument configuration particularly attractive to future biomedical applications.

Indexed as

MicroscopyMicroscopy, Scanning ProbeMechanical PhenomenaReproducibility of Resultsautomationfemtonewton resolutioninertial drivepiezo actuatorsSPMtranslation stagesvertical positioningvertical probes

Identifiers

PMID33925843
PMCPMC8123492
OpenAlexW3159235739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.