Evidence map›Paper›PMID 33925737›Full record

ArticleMolecules (Basel, Switzerland)2021

Keratin Scaffolds Containing Casomorphin Stimulate Macrophage Infiltration and Accelerate Full-Thickness Cutaneous Wound Healing in Diabetic Mice.

Marek Konop, Anna K Laskowska, Mateusz Rybka, Ewa Kłodzińska, Dorota Sulejczak, Robert A Schwartz, Joanna Czuwara

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Peptide-Based Approaches for Pain Relief and Healing in Wounds.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Marek KonopLaboratory of Centre for Preclinical Research (CePT), Department of Experimental Physiology and Pathophysiology, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-3914-6934
Anna K LaskowskaCentre for Preclinical Research and Technology (CePT), Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University of Warsaw, 02-091 Warsaw, Poland.
Mateusz RybkaLaboratory of Centre for Preclinical Research (CePT), Department of Experimental Physiology and Pathophysiology, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0003-0204-6101
Ewa KłodzińskaDepartment of Analytical Chemistry and Instrumental Analysis, Institute of Sport-National Research Institute, 03-301 Warsaw, Poland.ORCID 0000-0002-9931-5808
Dorota SulejczakDepartment of Experimental Pharmacology, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Robert A SchwartzDermatology and Pathology, Rutgers New Jersey Medical School, Newark, NJ 07103, USA.
Joanna CzuwaraDepartment of Dermatology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Medical University of Warsaw · PLInstytut Sportu · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PLRutgers, The State University of New Jersey · US

Funding

Warszawski Uniwersytet Medyczny 1S7/2/M/MB/N/20/20:MAT
6 · The paper itself

Abstract

Impaired wound healing is a major medical challenge, especially in diabetics. Over the centuries, the main goal of tissue engineering and regenerative medicine has been to invent biomaterials that accelerate the wound healing process. In this context, keratin-derived biomaterial is a promising candidate due to its biocompatibility and biodegradability. In this study, we evaluated an insoluble fraction of keratin containing casomorphin as a wound dressing in a full-thickness surgical skin wound model in mice (

Indexed as

Tissue EngineeringAnimalsBandagesCell ProliferationDiabetes Mellitus, ExperimentalEndorphinsHumansKeratinsMacrophagesMiceMice, Inbred NODSkinTissue ScaffoldsWound Healingbeta casomorphin 4027EndorphinsKeratinscasomorphindiabeteskeratin dressingopioidsskin wound healingtissue regeneration

Identifiers

PMID33925737
PMCPMC8125279
OpenAlexW3158680766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.