Evidence map›Paper›PMID 33925589›Full record

ArticleInternational journal of molecular sciences2021

A Gadolinium(III) Complex Based on the Thymine Nucleobase with Properties Suitable for Magnetic Resonance Imaging.

Marta Orts-Arroyo, Amadeo Ten-Esteve, Sonia Ginés-Cárdenas, Isabel Castro, Luis Martí-Bonmatí, José Martínez-Lillo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Article
  6. Metal Complexes in Diagnosis and Therapy.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marta Orts-ArroyoInstituto de Ciencia Molecular (ICMol), Universitat de València, c/Catedrático José Beltrán 2, Paterna, 46980 Valencia, Spain.
Amadeo Ten-EsteveRadiology Department and Biomedical Imaging Research Group (GIBI230), La Fe University and Polytechnic Hospital and La Fe Health Research Institute, 46026 Valencia, Spain.ORCID 0000-0002-3339-7767
Sonia Ginés-CárdenasRadiology Department and Biomedical Imaging Research Group (GIBI230), La Fe University and Polytechnic Hospital and La Fe Health Research Institute, 46026 Valencia, Spain.
Isabel CastroInstituto de Ciencia Molecular (ICMol), Universitat de València, c/Catedrático José Beltrán 2, Paterna, 46980 Valencia, Spain.ORCID 0000-0002-6046-3571
Luis Martí-BonmatíRadiology Department and Biomedical Imaging Research Group (GIBI230), La Fe University and Polytechnic Hospital and La Fe Health Research Institute, 46026 Valencia, Spain.ORCID 0000-0002-8234-010X
José Martínez-LilloInstituto de Ciencia Molecular (ICMol), Universitat de València, c/Catedrático José Beltrán 2, Paterna, 46980 Valencia, Spain.ORCID 0000-0003-1107-2344

Funding

Spanish Ministry of Science, Innovation and Universities CEX2019-000919-MSpanish Ministry of Science, Innovation and Universities Project PID2019-109735GB-I00VLC-BIOMED Program (2017) of the University of Valencia, Subprogram A "Ayudas para el fomento de acciones coordinadas UV-HUP/IIS La Fe" Project 11-2017-A
6 · The paper itself

Abstract

The paramagnetic gadolinium(III) ion is used as contrast agent in magnetic resonance (MR) imaging to improve the lesion detection and characterization. It generates a signal by changing the relaxivity of protons from associated water molecules and creates a clearer physical distinction between the molecule and the surrounding tissues. New gadolinium-based contrast agents displaying larger relaxivity values and specifically targeted might provide higher resolution and better functional images. We have synthesized the gadolinium(III) complex of formula [Gd(thy)

Indexed as

Contrast MediaCrystallography, X-RayGadoliniumHeterocyclic CompoundsMagnetic Resonance ImagingMagneticsMolecular StructureProtonsThymineWaterContrast MediaGadoliniumHeterocyclic CompoundsProtonsThymineWatercontrast agentcrystal structuregadoliniummagnetic resonancemetal complexesrelaxivitythymine

Identifiers

PMID33925589
PMCPMC8123898

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.