Evidence map›Paper›PMID 33925535›Full record

ArticleInternational journal of environmental research and public health2021

Biomarkers of Low-Level Environmental Exposure to Benzene and Oxidative DNA Damage in Primary School Children in Sardinia, Italy.

Ilaria Pilia, Marcello Campagna, Gabriele Marcias, Daniele Fabbri, Federico Meloni, Giovanna Spatari, Danilo Cottica, Claudio Cocheo, Elena Grignani, Fabio De-Giorgio and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Ilaria PiliaDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.ORCID 0000-0003-2834-5652
Marcello CampagnaDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
Gabriele MarciasDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
Daniele FabbriDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
Federico MeloniDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
Giovanna SpatariDepartment of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98122 Messina, Italy.
Danilo CotticaEnvironmental Research Centre, Istituti Clinici Scientifici Maugeri, 27100 Pavia, Italy.
Claudio CocheoEnvironmental Research Centre, Istituti Clinici Scientifici Maugeri, 27100 Pavia, Italy.
Elena GrignaniEnvironmental Research Centre, Istituti Clinici Scientifici Maugeri, 27100 Pavia, Italy.
Fabio De-GiorgioDepartment of Health Care Surveillance and Bioethics, Section of Legal Medicine, Università Cattolica del S. Cuore, 00168 Rome, Italy.
Pierluigi CoccoDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
Ernesto d'AlojaDepartment of Medical Sciences and Public Health, University of Cagliari, Monserrato, 092109 Cagliari, Italy.
University of Cagliari · ITIstituti Clinici Scientifici Maugeri · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main anthropic sources of exposure to airborne benzene include vehicular traffic, cigarette smoke, and industrial emissions.

methodsTo detect early genotoxic effects of environmental exposure to benzene, we monitored environmental, personal, and indoor airborne benzene in children living in an urban area and an area near a petrochemical plant. We also used urinary benzene and S-phenylmercapturic acid (S-PMA) as biomarkers of benzene exposure and urinary 8-hydroxydeoxyguanosine (8-OHdG) as a biomarker of early genotoxic effects.

resultsAlthough always below the European Union limit of 5 μg/m

conclusionsOur results suggest the importance of biological monitoring of low-level environmental exposure and its relation to risk of genotoxic effects among children.

Indexed as

BenzeneOccupational ExposureBiomarkersChildDNA DamageEnvironmental ExposureEnvironmental MonitoringHumansItalyOxidative StressSchoolsBenzeneBiomarkersbenzenebiological monitoringchildrenenvironmental exposuregenotoxicity

Identifiers

PMID33925535
PMCPMC8123794
OpenAlexW3159050839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.