Evidence map›Paper›PMID 33925461›Full record

ArticleInternational journal of molecular sciences2021

Hydroxyurea and Caffeine Impact pRb-like Protein-Dependent Chromatin Architecture Profiles in Interphase Cells of

Marcelina W Musiałek, Joanna Deckert, Dorota Rybaczek

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Effects of Elevated Temperature onInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Marcelina W MusiałekDepartment of Cytophysiology, Institute of Experimental Biology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0003-4014-7915
Joanna DeckertDepartment of Plant Ecophysiology, Institute of Experimental Biology, Faculty of Biology, Adam Mickiewicz University Poznań, Uniwersytetu Poznańskiego 6, 61-614 Poznań, Poland.ORCID 0000-0002-1676-6073
Dorota RybaczekDepartment of Cytophysiology, Institute of Experimental Biology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0002-9020-3391
University of Łódź · PLAdam Mickiewicz University in Poznań · PL

Funding

Fundacja na rzecz Nauki Polskiej POMOST/2011-4/8Narodowe Centrum Nauki PRELUDIUM NCN: 2019/35/N/NZ3/03915Wydział Biologii i Ochrony Środowiska, Uniwersytet Łódzki UŁ/505/378
6 · The paper itself

Abstract

The survival of cells depends on their ability to replicate correctly genetic material. Cells exposed to replication stress can experience a number of problems that may lead to deregulated proliferation, the development of cancer, and/or programmed cell death. In this article, we have induced prolonged replication arrest via hydroxyurea (HU) treatment and also premature chromosome condensation (PCC) by co-treatment with HU and caffeine (CF) in the root meristem cells of

Indexed as

CaffeineChromatinChromosomes, PlantCyclin D1DNA ReplicationHistonesHydroxyureaImage Processing, Computer-AssistedInterphasePlant CellsPlant ProteinsRetinoblastoma ProteinVicia fabaCaffeineChromatinCyclin D1HistonesHydroxyureaPlant ProteinsRetinoblastoma Protein3D modelingcaffeinecell cyclechromatin architectureheterochromatinhydroxyureaplantpremature chromosome condensationreplication stressretinoblastoma protein

Identifiers

PMID33925461
PMCPMC8123844
OpenAlexW3159491474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.