Evidence map›Paper›PMID 33925409›Full record

ArticleMolecules (Basel, Switzerland)2021

Stereoselective Synthesis of Selenium-Containing Glycoconjugates via the Mitsunobu Reaction.

Luigia Serpico, Mauro De Nisco, Flavio Cermola, Michele Manfra, Silvana Pedatella

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luigia SerpicoDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 4, I-80126 Napoli, Italy.
Mauro De NiscoDepartment of Sciences, University of Basilicata, Via dell'Ateneo Lucano 10, I-85100 Potenza, Italy.
Flavio CermolaDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 4, I-80126 Napoli, Italy.ORCID 0000-0003-0525-4520
Michele ManfraDepartment of Sciences, University of Basilicata, Via dell'Ateneo Lucano 10, I-85100 Potenza, Italy.
Silvana PedatellaDepartment of Chemical Sciences, University of Napoli Federico II, Via Cintia 4, I-80126 Napoli, Italy.ORCID 0000-0002-4078-1468

Funding

European Union - FSE, PON Ricerca e Innovazione 2014-2020 Azione I.1 Dottorati Innovativi con caratterizzazione Industriale
6 · The paper itself

Abstract

A simple and efficient route for the synthesis of new glycoconjugates has been developed. The approach acts as a model for a mini-library of compounds with a deoxy-selenosugar core joined to a polyphenolic moiety with well-known antioxidant properties. An unexpected stereocontrol detected in the Mitsunobu key reaction led to the most attractive product showing a natural d-configuration. Thus, we were able to obtain the target molecules from the commercially available d-ribose via a shorter and convenient sequence of reactions.

Indexed as

AntioxidantsGlycoconjugatesHumansOrganoselenium CompoundsSeleniumAntioxidantsGlycoconjugatesOrganoselenium CompoundsSeleniumantioxidantsmitsunobu reactionorganoselenium compoundsselenosugar

Identifiers

PMID33925409
PMCPMC8123786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.