ArticleNanomaterials (Basel, Switzerland)2021
Alkali-Treated Titanium Coated with a Polyurethane, Magnesium and Hydroxyapatite Composite for Bone Tissue Engineering.
Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 19 citations in OpenAlex.
- Anatase-Gentamicin Electrophoretic Coatings on Polyurethane-Modified Titanium: Antibacterial Performance, Biocompatibility, and Drug Delivery.International journal of biomaterials · 2026Article
- Magnesium-Titanium Alloys: A Promising Solution for Biodegradable Biomedical Implants.Materials (Basel, Switzerland) · 2024Review
- Influence of Anodizing Conditions on Biotribological and Micromechanical Properties of Ti-13Zr-13Nb Alloy.Materials (Basel, Switzerland) · 2023Article
- Novel Nano-Engineered Biomaterials for Bone Tissue Engineering.Nanomaterials (Basel, Switzerland) · 2022Article
- [Research progress on the effect of surface charge of biomaterials on bone formation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to form a functional layer on the surface of titanium (Ti) implants to enhance their bioactivity. Layers of polyurethane (PU), containing hydroxyapatite (HAp) nanoparticles (NPs) and magnesium (Mg) particles, were deposited on alkali-treated Ti surfaces using a cost-effective dip-coating approach. The coatings were assessed in terms of morphology, chemical composition, adhesion strength, interfacial bonding, and thermal properties. Additionally, cell response to the variably coated Ti substrates was investigated using MC3T3-E1 osteoblast-like cells, including assessment of cell adhesion, cell proliferation, and osteogenic activity through an alkaline phosphatase (ALP) assay. The results showed that the incorporation of HAp NPs enhanced the interfacial bonding between the coating and the alkali-treated Ti surface. Furthermore, the presence of Mg and HAp particles enhanced the surface charge properties as well as cell attachment, proliferation, and differentiation. Our results suggest that the deposition of a bioactive composite layer containing Mg and HAp particles on Ti implants may have the potential to induce bone formation.
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Registered trials
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