Evidence map›Paper›PMID 33925325›Full record

ArticleInternational journal of environmental research and public health2021

Parental Risk Factors and Child Birth Data in a Matched Year and Sex Group Cleft Population: A Case-Control Study.

Inês Francisco, Francisco Caramelo, Maria Helena Fernandes, Francisco Vale

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Inês FranciscoInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0002-3283-5104
Francisco CarameloInstitute of Clinical and Biomedical Research of Coimbra (iCBR), Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0002-0015-8604
Maria Helena FernandesFaculty of Dental Medicine, University of Porto, 4200-393 Porto, Portugal.ORCID 0000-0001-9391-9574
Francisco ValeInstitute of Orthodontics, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0003-2615-2929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The etiology of orofacial cleft (OC) is not completely known but several genetic and environmental risk factors have been identified. Moreover, a knowledge gap still persists regarding neonatal characteristics. This study evaluated the effect of parental age and mothers' body mass index on the risk of having an OC child, in a matched year and sex group (cleft/healthy control). Additionally, birth data were analyzed between groups. (2) Methods: 266 individuals born between 1995 to 2015 were evaluated: 133 OC individuals (85 males/48 females) and 133 control (85 males/48 females). A logistic model was used for the independent variables. ANOVA or Kruskal-Wallis tests were used for comparison between the OC phenotypes. (3) Results: Regarding statistically significant parental related factors, the probability of having a cleft child decreases for each maternal year increase (odds ratio = 0.903) and increases for each body mass index unit (kg/m

Indexed as

Cleft LipCleft PalateCase-Control StudiesChildFemaleHumansInfant, NewbornMaleParturitionPregnancyRisk Factorsbody mass indexchild birth datacleft lipcleft palateenvironmental risk factorsparental age

Identifiers

PMID33925325
PMCPMC8123601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.