Evidence map›Paper›PMID 33925248›Full record

ArticleBiology2021

Reduced Retinal Degeneration in an Oxidative Stress Organ Culture Model through an iNOS-Inhibitor.

Ana M Mueller-Buehl, Teresa Tsai, José Hurst, Carsten Theiss, Laura Peters, Lisa Hofmann, Fenja Herms, Sandra Kuehn, Sven Schnichels, Stephanie C Joachim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  13. [Are organ and co-cultures an alternative to animal models in ophthalmology?]Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ana M Mueller-BuehlExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
Teresa TsaiExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
José HurstCenter for Ophthalmology Tübingen, University Eye Hospital Tübingen, 72076 Tübingen, Germany.
Carsten TheissDepartment of Cytology, Institute of Anatomy, Ruhr-University Bochum, 44801 Bochum, Germany.ORCID 0000-0001-7983-0143
Laura PetersExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
Lisa HofmannExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
Fenja HermsExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
Sandra KuehnExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.
Sven SchnichelsCenter for Ophthalmology Tübingen, University Eye Hospital Tübingen, 72076 Tübingen, Germany.
Stephanie C JoachimExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, In der Schornau 23-25, 44892 Bochum, Germany.ORCID 0000-0001-7056-0829
University Hospitals of the Ruhr-University of Bochum · DESTZ eyetrial · DERuhr University Bochum · DEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

FoRUM (Ruhr-University Bochum, Germany) noneStiftung zur Förderung der Erforschung von Ersatz- und Ergänzungsmethoden zur Einschränkung von Tierversuchen none
6 · The paper itself

Abstract

In retinal organ cultures, H

Indexed as

apoptosisautophagyiNOS-inhibitoroxidative stressporcine organ culture model

Identifiers

PMID33925248
PMCPMC8145164
OpenAlexW3159678742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.