Evidence map›Paper›PMID 33925062›Full record

ReviewInternational journal of molecular sciences2021

Date Palm Fruit (

Yousef A Al-Dashti, Roberta R Holt, Carl L Keen, Robert M Hackman

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Valorization of Date Palm (Molecules (Basel, Switzerland) · 2026
    Review
  6. Nutraceuticals ofDrug design, development and therapy · 2026
    Review
  7. Review
  8. Article
  9. Therapeutic Power of Date Fruit (Food science & nutrition · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Hypoglycemic and Hypolipidemic Effects ofJournal of experimental pharmacology · 2025
    Article
  14. Article
  15. Article
  16. Unveiling the Neuroprotective Potential of Date Palm (Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Date Palm Fruit (Nutrients · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yousef A Al-DashtiDepartment of Food and Nutrition Science, College of Health Sciences, Public Authority for Applied Education and Training, Shuwaikh 70654, Kuwait.
Roberta R HoltDepartment of Nutrition, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
Carl L KeenDepartment of Nutrition, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
Robert M HackmanDepartment of Nutrition, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
University of California, Davis · USPublic Authority for Applied Education and Training · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is a leading cause of death globally, presenting an immense public and economic burden. Studies on cardioprotective foods and their bioactive components are needed to address both personal and public health needs. Date fruit is rich in polyphenols, particularly flavonoids, certain micronutrients, and dietary fiber, which can impact vascular health, and have the potential to attenuate vascular disease in humans. Data from in vitro and animal studies report that consumption of date fruit or extracts can modulate select markers of vascular health, particularly plasma lipid levels including triglycerides and cholesterol, indices of oxidative stress and inflammation, but human data is scant. More investigation is needed to better characterize date polyphenols and unique bioactive compounds or fractions, establish safe and effective levels of intake, and delineate underlying mechanisms of action. Implementing scientific rigor in clinical trials and assessment of functional markers of vascular disease, such as flow-mediated dilation and peripheral arterial tonometry, along with gut microbiome profiles would provide useful information with respect to human health. Emerging data supports the notion that intake of date fruit and extracts can be a useful component of a healthy lifestyle for those seeking beneficial effects on vascular health.

Indexed as

Diet, HealthyFruitPhoeniceaeAnimalsCardiotonic AgentsCardiovascular DiseasesFemaleHumansLipidsMalePlant ExtractsPolyphenolsCardiotonic AgentsLipidsPlant ExtractsPolyphenolscardiovascularendothelial functionflavonoidsinflammationlipidsoxidative stresspolyphenols

Identifiers

PMID33925062
PMCPMC8125345
OpenAlexW3158523687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.