Evidence map›Paper›PMID 33925025›Full record

ArticleInternational journal of molecular sciences2021

The Role of Nonshivering Thermogenesis Genes on Leptin Levels Regulation in Residents of the Coldest Region of Siberia.

Alena A Nikanorova, Nikolay A Barashkov, Vera G Pshennikova, Sergey S Nakhodkin, Nyurgun N Gotovtsev, Georgii P Romanov, Aisen V Solovyev, Sargylana S Kuzmina, Nikolay N Sazonov, Sardana A Fedorova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alena A NikanorovaLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.ORCID 0000-0002-7129-6633
Nikolay A BarashkovLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.ORCID 0000-0002-6984-7934
Vera G PshennikovaLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.ORCID 0000-0001-6866-9462
Sergey S NakhodkinLaboratory of Molecular Biology, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, Sakha Republic (Yakutia), Russia.
Nyurgun N GotovtsevLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.
Georgii P RomanovLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.ORCID 0000-0002-2936-5818
Aisen V SolovyevLaboratory of Molecular Genetics, Yakut Science Centre of Complex Medical Problems, 677010 Yakutsk, Sakha Republic (Yakutia), Russia.
Sargylana S KuzminaLaboratory of Molecular Biology, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, Sakha Republic (Yakutia), Russia.
Nikolay N SazonovLaboratory of Molecular Biology, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, Sakha Republic (Yakutia), Russia.
Sardana A FedorovaLaboratory of Molecular Biology, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, Sakha Republic (Yakutia), Russia.
North-Eastern Federal University · RUAcademy of Sciences of the Republic of Sakha · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptin plays an important role in thermoregulation and is possibly associated with the microevolutionary processes of human adaptation to a cold climate. In this study, based on the Yakut population (

Indexed as

Cold ClimateAcclimatizationAdolescentBody Mass IndexBrain-Derived Neurotrophic FactorEvolution, MolecularFemaleGenotypeHumansIndigenous PeoplesLeptinMalePolymorphism, Single NucleotideSelection, GeneticSiberiaThermogenesisBDNF protein, humanBrain-Derived Neurotrophic FactorLEP protein, humanLeptinUCP1 protein, humanUncoupling Protein 1adaptationadipose tissuecold climateleptinnonshivering thermogenesisRussiaSiberiaUCP1Yakut population

Identifiers

PMID33925025
PMCPMC8124869
OpenAlexW3158341606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.