Evidence map›Paper›PMID 33924983›Full record

ReviewBiomedicines2021

Optoacoustic Imaging in Inflammation.

Adrian P Regensburger, Emma Brown, Gerhard Krönke, Maximilian J Waldner, Ferdinand Knieling

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05160077 (Noninvasive Characterization of Postprandial Intestinal Blood Flow Using Multispectral Optoacoustic Tomography), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05160077 nacompletednot on this map

Noninvasive Characterization of Postprandial Intestinal Blood Flow Using Multispectral Optoacoustic Tomography

TypeinterventionalSponsorUniversity of Erlangen-Nürnberg Medical SchoolRan2021 to 2022Enrolled10ConditionsDigestive System Disease, Inflammatory Bowel DiseasesArmsMultispectral optoacoustic tomography (MSOT)
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Photoacoustic imaging of intestinal physiological biomarkers in infants and children.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Article
  5. Article
  6. Optoacoustic muscle imaging.Journal of neuromuscular diseases · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Kinin BInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Imaging in psoriatic arthritis: established methods and emerging techniques.Therapeutic advances in musculoskeletal disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Adrian P RegensburgerDepartment of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Loschgestr. 15, D-91054 Erlangen, Germany.
Emma BrownDepartment of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.
Gerhard KrönkeDepartment of Medicine 3, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Ulmenweg 18, D-91054 Erlangen, Germany.
Maximilian J WaldnerDepartment of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Ulmenweg 18, D-91054 Erlangen, Germany.
Ferdinand KnielingDepartment of Pediatrics and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Loschgestr. 15, D-91054 Erlangen, Germany.ORCID 0000-0002-3535-2626
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Cambridge · GB

Funding

Else Kröner-Fresenius-Stiftung 2018_EKMS.03Horizon 2020 Framework Programme 830965Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Erlangen Clinician Scientist ProgrammeMedizinische Fakultät, Friedrich-Alexander-Universität Erlangen-Nürnberg ELAN Fond P055
6 · The paper itself

Abstract

Optoacoustic or photoacoustic imaging (OAI/PAI) is a technology which enables non-invasive visualization of laser-illuminated tissue by the detection of acoustic signals. The combination of "light in" and "sound out" offers unprecedented scalability with a high penetration depth and resolution. The wide range of biomedical applications makes this technology a versatile tool for preclinical and clinical research. Particularly when imaging inflammation, the technology offers advantages over current clinical methods to diagnose, stage, and monitor physiological and pathophysiological processes. This review discusses the clinical perspective of using OAI in the context of imaging inflammation as well as in current and emerging translational applications.

Indexed as

acute inflammationchronic inflammationimaging inflammationmolecular imagingMSOToptoacousticsPAIphotoacousticsRSOM

Identifiers

PMID33924983
PMCPMC8145174
OpenAlexW3159210803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.