Evidence map›Paper›PMID 33924804›Full record

ReviewInternational journal of molecular sciences2021

Emerging Emulsifiers: Conceptual Basis for the Identification and Rational Design of Peptides with Surface Activity.

Fabian Ricardo, Diego Pradilla, Juan C Cruz, Oscar Alvarez

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  3. Molecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabian RicardoDepartment of Chemical and Food Engineering, Universidad de los Andes, Bogotá 111711, Colombia.ORCID 0000-0002-1795-6223
Diego PradillaDepartment of Chemical and Food Engineering, Universidad de los Andes, Bogotá 111711, Colombia.ORCID 0000-0001-8810-9526
Juan C CruzDepartment of Biomedical Engineering, Universidad de los Andes, Bogotá 111711, Colombia.ORCID 0000-0002-7790-7546
Oscar AlvarezDepartment of Chemical and Food Engineering, Universidad de los Andes, Bogotá 111711, Colombia.ORCID 0000-0002-5486-5240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emulsifiers are gradually evolving from synthetic molecules of petrochemical origin to biomolecules mainly due to health and environmental concerns. Peptides represent a type of biomolecules whose molecular structure is composed of a sequence of amino acids that can be easily tailored to have specific properties. However, the lack of knowledge about emulsifier behavior, structure-performance relationships, and the implementation of different design routes have limited the application of these peptides. Some computational and experimental approaches have tried to close this knowledge gap, but restrictions in understanding the fundamental phenomena and the limited property data availability have made the performance prediction for emulsifier peptides an area of intensive research. This study provides the concepts necessary to understand the emulsifying behavior of peptides. Additionally, a straightforward description is given of how the molecular structure and conditions of the system directly impact the peptides' ability to stabilize emulsion droplets. Moreover, the routes to design and discover novel peptides with interfacial and emulsifying activity are also discussed, along with the strategies to address some of their major pitfalls and challenges. Finally, this contribution reviews methodologies to build and use data sets containing standard properties of emulsifying peptides by looking at successful applications in different fields.

Indexed as

Computer-Aided DesignEmulsifying AgentsPeptidesEmulsifying AgentsPeptidesemulsifier peptideemulsionpeptide designsurface tensionsurfactant

Identifiers

PMID33924804
PMCPMC8124350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.