Evidence map›Paper›PMID 33924772›Full record

ReviewInternational journal of molecular sciences2021

From Channels to Canonical Wnt Signaling: A Pathological Perspective.

Silvia Muccioli, Valentina Brillo, Leonardo Chieregato, Luigi Leanza, Vanessa Checchetto, Roberto Costa

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Silvia MuccioliDepartment of Biology, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-0544-6808
Valentina BrilloDepartment of Biology, University of Padova, 35122 Padova, Italy.
Leonardo ChieregatoDepartment of Biology, University of Padova, 35122 Padova, Italy.
Luigi LeanzaDepartment of Biology, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-5919-7114
Vanessa ChecchettoDepartment of Biology, University of Padova, 35122 Padova, Italy.
Roberto CostaDepartment of Biology, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-7328-9018
University of Padua · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 23271Università degli Studi di Padova BIRD162511
6 · The paper itself

Abstract

Wnt signaling is an important pathway mainly active during embryonic development and controlling cell proliferation. This regulatory pathway is aberrantly activated in several human diseases. Ion channels are known modulators of several important cellular functions ranging from the tuning of the membrane potential to modulation of intracellular pathways, in particular the influence of ion channels in Wnt signaling regulation has been widely investigated. This review will discuss the known links between ion channels and canonical Wnt signaling, focusing on their possible roles in human metabolic diseases, neurological disorders, and cancer.

Indexed as

Wnt Signaling PathwayAnimalsDiseaseHumansIon ChannelsIon Channelscancerion channelsmetabolic diseasesneurological disordersWnt signaling

Identifiers

PMID33924772
PMCPMC8125460
OpenAlexW3157604996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.