Evidence map›Paper›PMID 33924735›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design.

Rui Huang, David C Luther, Xianzhi Zhang, Aarohi Gupta, Samantha A Tufts, Vincent M Rotello

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Nanoparticles to target asthma.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  4. Review
  5. Review
  6. Modular Fabrication of Bioorthogonal Nanozymes for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  7. Article
  8. Article
  9. The Why and How of Ultrasmall Nanoparticles.Accounts of chemical research · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rui HuangDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.ORCID 0000-0002-1535-9804
David C LutherDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.ORCID 0000-0002-4697-8683
Xianzhi ZhangDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.ORCID 0000-0002-9585-7458
Aarohi GuptaDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.ORCID 0000-0003-1303-1159
Samantha A TuftsDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.
Vincent M RotelloDepartment of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA.ORCID 0000-0002-5184-5439

Funding

NIH HHS DK121351, AI134770, and EB022641
6 · The paper itself

Abstract

Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with "small" organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine.

Indexed as

bacterial biofilmbioorthogonal catalysisdrug deliveryinorganic nanoparticlesmonolayersnanozymepeptide and proteinsstimuli-responsivesurface chemistrytumors

Identifiers

PMID33924735
PMCPMC8069843

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.