Evidence map›Paper›PMID 33924670›Full record

ArticleBiomedicines2021

MicroRNAs Regulating Tumor and Immune Cell Interactions in the Prediction of Relapse in Early Stage Breast Cancer.

Chara Papadaki, Konstantina Thomopoulou, Alexia Monastirioti, George Koronakis, Maria A Papadaki, Konstantinos Rounis, Lambros Vamvakas, Christoforos Nikolaou, Dimitrios Mavroudis, Sofia Agelaki

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chara PapadakiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Vassilika Vouton, 71003 Crete, Greece.ORCID 0000-0002-4591-3757
Konstantina ThomopoulouDepartment of Medical Oncology, University General Hospital of Heraklion, Vassilika Vouton, 71110 Crete, Greece.
Alexia MonastiriotiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Vassilika Vouton, 71003 Crete, Greece.
George KoronakisDepartment of Medical Oncology, University General Hospital of Heraklion, Vassilika Vouton, 71110 Crete, Greece.
Maria A PapadakiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Vassilika Vouton, 71003 Crete, Greece.ORCID 0000-0002-6363-7258
Konstantinos RounisDepartment of Medical Oncology, University General Hospital of Heraklion, Vassilika Vouton, 71110 Crete, Greece.ORCID 0000-0002-6643-9855
Lambros VamvakasDepartment of Medical Oncology, University General Hospital of Heraklion, Vassilika Vouton, 71110 Crete, Greece.
Christoforos NikolaouDepartment of Biology, University of Crete, Heraklion, Vassilika Vouton, 70013 Crete, Greece.ORCID 0000-0003-3001-6786
Dimitrios MavroudisLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Vassilika Vouton, 71003 Crete, Greece.
Sofia AgelakiLaboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Vassilika Vouton, 71003 Crete, Greece.
University of Crete · GRUniversity Hospital of Heraklion · GR

Funding

ANTICANCER RESEARCH SUPPORT ASSOCIATION (ARSA). N/AHELLENIC SOCIETY OF MEDICAL ONCOLOGY (HESMO) NA
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are involved in the regulation of immune response and hold an important role in tumor immune escape. We investigated the differential expression of the immunomodulatory miR-10b, miR-19a, miR-20a, miR-126, and miR-155 in the plasma of healthy women and patients with early stage breast cancer and interrogated their role in the prediction of patients' relapse. Blood samples were obtained from healthy women (

Indexed as

antitumor immune responsecirculating miRNAsearly breast cancerimmune escapeimmune surveillancerelapse

Identifiers

PMID33924670
PMCPMC8069787
OpenAlexW3154614146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.