Evidence map›Paper›PMID 33924642›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Therapeutic Potential and Immunomodulatory Role of Coenzyme Q

Chary López-Pedrera, José Manuel Villalba, Alejandra Mª Patiño-Trives, Maria Luque-Tévar, Nuria Barbarroja, Mª Ángeles Aguirre, Alejandro Escudero-Contreras, Carlos Pérez-Sánchez

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05871086 (The Effect of Coenzyme Q10 Supplementation on the Clinical Outcome of Juvenile Idiopathic Arthritis Patients), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05871086 phase2 / phase3unknown statusnot on this mapstarted 2023, after this paper: background citation

The Effect of Coenzyme Q10 Supplementation on the Clinical Outcome of Juvenile Idiopathic Arthritis Patients

TypeinterventionalSponsorNourhan ElsherifRan2023 to 2023Enrolled60ConditionsJuvenile Idiopathic ArthritisArmsCoenzyme Q10, Placebo, Standard Regimen
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Trained immunity in respiratory diseases: Mechanisms of action and intervention strategies.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  3. Article
  4. Mitochondria as a Therapeutic Target in Metabolic Disorders.Mini reviews in medicinal chemistry · 2026
    Review
  5. Review
  6. Overview of Oxidative Stress in Systemic Lupus Erythematosus.Antioxidants (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Coenzyme Q10 Stimulate Reproductive Vatality.Drug design, development and therapy · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Coenzyme Q at the Hinge of Health and Metabolic Diseases.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chary López-PedreraRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.ORCID 0000-0003-2067-4603
José Manuel VillalbaDepartment of Cell Biology, Immunology and Physiology, Agrifood Campus of International Excellence, University of Córdoba, ceiA3, 14014 Córdoba, Spain.ORCID 0000-0001-8554-3802
Alejandra Mª Patiño-TrivesRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.
Maria Luque-TévarRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.
Nuria BarbarrojaRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.
Mª Ángeles AguirreRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.
Alejandro Escudero-ContrerasRheumatology Service, Reina Sofia Hospital/Maimonides Institute for Research in Biomedicine of Córdoba (IMIBIC), University of Córdoba, 14004 Córdoba, Spain.ORCID 0000-0001-5891-5527
Carlos Pérez-SánchezDepartment of Cell Biology, Immunology and Physiology, Agrifood Campus of International Excellence, University of Córdoba, ceiA3, 14014 Córdoba, Spain.ORCID 0000-0002-1903-5970
Instituto Maimónides de Investigación Biomédica de Córdoba · ESUniversity of Córdoba · ES

Funding

Instituto de Salud Carlos III PI18/00837Instituto de Salud Carlos III RD16/0012/0015Junta de Andalucía P18-RT-4264, 1263735-R and BIO-276Servicio Andaluz de Salud PI-0285-2017Spanish Ministerio de Ciencia, Innovación y Universidades (MICIU) RTI2018-100695-B-I00
6 · The paper itself

Abstract

Coenzyme Q

Indexed as

autoimmune disorderscardiovascular diseasecoenzyme Q10inflammation

Identifiers

PMID33924642
PMCPMC8069673
OpenAlexW3153915966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.