Evidence map›Paper›PMID 33924500›Full record

ArticleJournal of clinical medicine2021

Potential Non-Invasive Biomarkers for Early Diagnosis of Oral Squamous Cell Carcinoma.

Valentina Dikova, Eloisa Jantus-Lewintre, Jose Bagan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  9. The Role of Proinflammatory Biomarkers in Oral Cancer Pathophysiology.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Valentina DikovaFaculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-5081-7981
Eloisa Jantus-LewintreMolecular Oncology Laboratory FIHGUV, 46014 Valencia, Spain.ORCID 0000-0001-7395-4380
Jose BaganFaculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.
Universitat de València · ESFundacio Investigacio Hospital General Universitari De Valencia · ES

Funding

Horizon 2020 European Union's Horizon 2020 Research and Innovation programme under the MSC Grant Agreement № 721906
6 · The paper itself

Abstract

This study aimed to investigate the role of a panel of salivary cytokines as biomarkers for early detection oral squamous cell carcinoma (OSCC), comparing their levels among healthy individuals, patients with oral leukoplakia (OL), and malignant lesions. Cytokine profiling analysis performed in a minimally invasive sample was correlated with clinicopathological variables in our patient cohorts. Unstimulated saliva was obtained from subjects with OSCC at early (

Indexed as

non-invasive biomarkersoral canceroral leukoplakiasaliva testingtranslational research

Identifiers

PMID33924500
PMCPMC8070511
OpenAlexW3156409570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.