Evidence map›Paper›PMID 33924354›Full record

ArticleNutrients2021

Bioflavonoid Robinin from

Lia Tsiklauri, Karol Švík, Martin Chrastina, Silvester Poništ, František Dráfi, Lukáš Slovák, Mery Alania, Ether Kemertelidze, Katarina Bauerova

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Nutrients · 2023
    Article
  7. Enhanced Anti-Inflammatory Effect of the Combination ofMolecules (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Mechanism of Action of Flavonoids ofMolecules (Basel, Switzerland) · 2022
    Article
  11. FermentedFrontiers in nutrition · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Lia TsiklauriIovel Kutateladze Pharmacochemistry Institute, Tbilisi State Medical University, P. Sarajishvilist 36, Tbilisi 0159, Georgia.ORCID 0000-0002-7808-5329
Karol ŠvíkCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.
Martin ChrastinaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.
Silvester PoništCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.
František DráfiCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.ORCID 0000-0001-9287-5514
Lukáš SlovákCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.
Mery AlaniaIovel Kutateladze Pharmacochemistry Institute, Tbilisi State Medical University, P. Sarajishvilist 36, Tbilisi 0159, Georgia.
Ether KemertelidzeIovel Kutateladze Pharmacochemistry Institute, Tbilisi State Medical University, P. Sarajishvilist 36, Tbilisi 0159, Georgia.
Katarina BauerovaCentre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská cesta 9, 84104 Bratislava, Slovakia.
Slovak Academy of Sciences · SKTbilisi State Medical University · GE

Funding

Agentúra na Podporu Výskumu a Vývoja APVV-15-0308Vedecká Grantová Agentúra MŠVVaŠ SR a SAV VEGA 2/0115/19Vedecká Grantová Agentúra MŠVVaŠ SR a SAV VEGA 2/0136/20
6 · The paper itself

Abstract

Anti-inflammatory potential of orally administrated bioflavonoid-robinin, active sub-stance of original drug Flaroninum™ (FL), was investigated in the combination with methotrexate (MTX) and in monotherapy in rats suffering from adjuvant-induced arthritis (AA). Robinin (kaempferol-3-

Indexed as

AnimalsAnti-Inflammatory AgentsArthritis, ExperimentalArthritis, RheumatoidAstragalus PlantDrug SynergismDrug Therapy, CombinationFlavonoidsFlowersFreund's AdjuvantHumansLipidsMaleMethotrexatePlant LeavesRatsAnti-Inflammatory AgentsFlavonoidsFreund's Adjuvantincomplete Freund's adjuvantLipidsMethotrexaterobininarthritisastragalusflavonoidsmethotrexaterobinin

Identifiers

PMID33924354
PMCPMC8069410
OpenAlexW3153417161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.