Evidence map›Paper›PMID 33924085›Full record

ArticleCells2021

Proteome Damage Inflicted by Ionizing Radiation: Advancing a Theme in the Research of Miroslav Radman.

Steven T Bruckbauer, Benjamin B Minkoff, Michael R Sussman, Michael M Cox

Abstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven T BruckbauerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0002-1684-8466
Benjamin B MinkoffCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-9807-0354
Michael R SussmanDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-9374-3353
Michael M CoxDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0003-3606-5722

Funding

Molecular basis of ionizing radiation resistanceR01GM112757 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COX, MICHAEL M. · 2017 to 2020
$1.2M
NIGMS NIH HHS GM112757NIGMS NIH HHS R01 GM112757
6 · The paper itself

Abstract

Oxidative proteome damage has been implicated as a major contributor to cell death and aging. Protein damage and aging has been a particular theme of the recent research of Miroslav Radman. However, the study of how cellular proteins are damaged by oxidative processes is still in its infancy. Here we examine oxidative changes in the proteomes of four bacterial populations-wild type

Indexed as

Radiation, IonizingResearchEscherichia coliEscherichia coli ProteinsOxidation-ReductionPeptidesProteomeEscherichia coli ProteinsPeptidesProteomeDeinococcus radioduransEscherichia coliionizing radiationprotein damageproteomereactive oxygen species

Identifiers

PMID33924085
PMCPMC8074248

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.