Evidence map›Paper›PMID 33924041›Full record

ArticleToxins2021

Vasoactive Effects of Acute Ergot Exposure in Sheep.

Rossalin Yonpiam, Jair Gobbet, Ashok Jadhav, Kaushik Desai, Barry Blakley, Ahmad Al-Dissi

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rossalin YonpiamDepartment of Veterinary Pathology, Western College of Veterinary Medicine; University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.
Jair GobbetDepartment of Veterinary Pathology, Western College of Veterinary Medicine; University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.
Ashok JadhavDepartment of Pharmacology, College of Medicine University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Kaushik DesaiDepartment of Pharmacology, College of Medicine University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.
Barry BlakleyDepartment of Veterinary Biomedical Sciences, Western College of Veterinary Medicine; University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.
Ahmad Al-DissiDepartment of Veterinary Pathology, Western College of Veterinary Medicine; University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada.
University of Saskatchewan · CA

Funding

The Saskatchewan Ministry of Agriculture-Agriculture Development Fund (ADF) 20140186
6 · The paper itself

Abstract

Ergotism is a common and increasing problem in Saskatchewan's livestock. Chronic exposure to low concentrations of ergot alkaloids is known to cause severe arterial vasoconstriction and gangrene through the activation of adrenergic and serotonergic receptors on vascular smooth muscles. The acute vascular effects of a single oral dose with high-level exposure to ergot alkaloids remain unknown and are examined in this study. This study had two main objectives; the first was to evaluate the role of α

Indexed as

Adrenergic alpha-1 Receptor AntagonistsAnimalsArteriesErgot AlkaloidsErgotismFemaleHindlimbMuscle, Smooth, VascularPrazosinReceptors, Adrenergic, alpha-1Sheep, DomesticSignal TransductionVasoconstrictionVasoconstrictor AgentsAdrenergic alpha-1 Receptor AntagonistsErgot AlkaloidsPrazosinReceptors, Adrenergic, alpha-1TerazosinVasoconstrictor Agentsacute ergot exposureadrenergic receptorsergot toxicitysheepvasoconstriction

Identifiers

PMID33924041
PMCPMC8072561
OpenAlexW3156681779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.