Evidence map›Paper›PMID 33923965›Full record

ArticleCancers2021

Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA-A Proof of Concept Study.

Falco Reissig, David Bauer, Kristof Zarschler, Zbynek Novy, Katerina Bendova, Marie-Charlotte Ludik, Klaus Kopka, Hans-Jürgen Pietzsch, Milos Petrik, Constantin Mamat

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Potency and safety of novel [British journal of cancer · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. It's a match: use of the radionuclide theranostic pairEJNMMI radiopharmacy and chemistry · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Ac-225 radiochemistry through the lens of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  13. Article
  14. Article
  15. Scalability study on [EJNMMI radiopharmacy and chemistry · 2024
    Article
  16. Article
  17. Development ofJournal of nanobiotechnology · 2024
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Falco ReissigHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.ORCID 0000-0002-5203-0776
David BauerHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.ORCID 0000-0002-3051-7997
Kristof ZarschlerHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.ORCID 0000-0002-7571-4732
Zbynek NovyInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 1333/5, 779 00 Olomouc, Czech Republic.ORCID 0000-0002-7716-2142
Katerina BendovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 1333/5, 779 00 Olomouc, Czech Republic.
Marie-Charlotte LudikHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.
Klaus KopkaHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.ORCID 0000-0003-4846-1271
Hans-Jürgen PietzschHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.
Milos PetrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 1333/5, 779 00 Olomouc, Czech Republic.ORCID 0000-0003-1334-5916
Constantin MamatHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstraße 400, D-01328 Dresden, Germany.ORCID 0000-0003-1906-3186
Helmholtz-Zentrum Dresden-Rossendorf · DEInstitute of Molecular and Translational Medicine · CZ

Funding

European Regional Development Fund CZ.02.1.01/0.0/0.0/16_019/0000868Ministerstvo Školství, Mládeže a Tělovýchovy LM2018133
6 · The paper itself

Abstract

Currently, targeted alpha therapy is one of the most investigated topics in radiopharmaceutical cancer management. Especially, the alpha emitter

Indexed as

actinium-225click chemistryPSMAtargeted alpha therapytheranostics

Identifiers

PMID33923965
PMCPMC8073976
OpenAlexW3154498869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.