Evidence map›Paper›PMID 33923741›Full record

ArticleMicroorganisms2021

Evaluation of Thymol-β-d-Glucopyranoside as a Potential Prebiotic Intervention to Reduce Carriage of Zoonotic Pathogens in Weaned and Feeder Pigs.

Gizem Levent, Robin C Anderson, Branko Petrujkić, Toni L Poole, Haiqi He, Kenneth J Genovese, Michael E Hume, Ross C Beier, Roger B Harvey, David J Nisbet

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Unveiling the Neem (Plants (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Antagonistic Effects of Lipids Against the Anti-Frontiers in veterinary science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Gizem LeventUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.ORCID 0000-0001-9207-9999
Robin C AndersonUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Branko PetrujkićUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.ORCID 0000-0002-3112-4589
Toni L PooleUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Haiqi HeUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Kenneth J GenoveseUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Michael E HumeUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Ross C BeierUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.ORCID 0000-0002-3445-1008
Roger B HarveyUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
David J NisbetUnited States Department of Agriculture, Agricultural Research Service, Food and Feed Safety Research Unit, College Station, TX 77845, USA.
Agricultural Research Service · US

Funding

National Pork Board Grant 14-077
6 · The paper itself

Abstract

The gut of food-producing animals is a reservoir for foodborne pathogens. Thymol is bactericidal against foodborne pathogens but rapid absorption of thymol from the proximal gut precludes the delivery of effective concentrations to the lower gut where pathogens mainly colonize. Thymol-β-d-glucopyranoside is reported to be more resistant to absorption than thymol in everted jejunal segments and could potentially function as a prebiotic by resisting degradation and absorption in the proximal gut but being hydrolysable by microbial β-glycosidase in the distal gut. Previous in vitro studies showed bactericidal effects of thymol-β-d-glucopyranoside against

Indexed as

CampylobacterEscherichia coliSalmonellaswinethymolthymol-β-d-glucopyranoside

Identifiers

PMID33923741
PMCPMC8073024
OpenAlexW3155462407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.