Evidence map›Paper›PMID 33923737›Full record

ReviewCancers2021

Iatrogenic Ocular Surface Diseases Occurring during and/or after Different Treatments for Ocular Tumours.

Giuseppe Giannaccare, Federico Bernabei, Martina Angi, Marco Pellegrini, Antonio Maestri, Vito Romano, Vincenzo Scorcia, Pierre-Räphael Rothschild

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Giuseppe GiannaccareDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0003-2617-0289
Federico BernabeiService d'ophtalmologie, Ophtalmopôle de Paris, Hôpital Cochin, AP-HP, F-75014 Paris, France.
Martina AngiOcular Oncology Service, Department of Surgical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumouri, 20133 Milan, Italy.
Marco PellegriniOphthalmology Unit, S.Orsola-Malpighi University Hospital, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-6419-6941
Antonio MaestriMedical Oncology Department, Santa Maria della Scaletta Hospital, 40026 Imola, Italy.
Vito RomanoDepartment of Corneal and External Eye Diseases, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.ORCID 0000-0002-5148-7643
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Græcia of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Pierre-Räphael RothschildService d'ophtalmologie, Ophtalmopôle de Paris, Hôpital Cochin, AP-HP, F-75014 Paris, France.ORCID 0000-0003-4984-4768
Magna Graecia University · ITFondazione IRCCS Istituto Nazionale dei Tumori · ITHôpital Cochin · FRInserm · FRSanta Maria Nuova Hospital · ITUniversity of Bologna · ITUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ocular surface represents a finely regulated system that allows the protection of the eye. It is particularly susceptible to different treatments for intraocular tumours, such as uveal melanoma and conjunctival cancers. Traditionally, the management of ocular tumours depends on the characteristics of the lesion, and is based on a combination of selective surgery, topical chemotherapy, and/or radiotherapy delivered through different mechanisms (e.g., charged-particle radiotherapy or brachytherapy). Possible complications involving the ocular surface range from transient dry eye disease or keratitis up to corneal melting and perforation, which in any case deserve careful evaluation for the risk of permanent sigh-threatening complications. Clinicians involved in the management of these patients must be aware of this risk, in order to reach an early diagnosis and promptly set up an adequate treatment. The present review of the literature will summarize acute and chronic complications affecting the ocular surface following different therapies for the treatment of ocular tumours.

Indexed as

anti-cancer agentschoroidal melanomacomplicationsdry eyeocular surfaceocular surface squamous neoplasiaocular tumoursradiotherapyuveal melanoma

Identifiers

PMID33923737
PMCPMC8073875
OpenAlexW3155197023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.