Evidence map›Paper›PMID 33923700›Full record

ArticleInternational journal of molecular sciences2021

Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release.

Bernhard Friedrich, Jean-Philippe Auger, Silvio Dutz, Iwona Cicha, Eveline Schreiber, Julia Band, Aldo R Boccacccini, Gerhard Krönke, Christoph Alexiou, Rainer Tietze

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Bernhard FriedrichDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.ORCID 0000-0003-3845-9135
Jean-Philippe AugerDepartment of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen and Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Silvio DutzInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, 98693 Ilmenau, Germany.ORCID 0000-0002-7258-0943
Iwona CichaDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.ORCID 0000-0002-7399-5307
Eveline SchreiberDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Julia BandDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Aldo R BoccaccciniInstitute of Biomaterials, Department of Materials Science and Engineering, FAU, 91058 Erlangen, Germany.ORCID 0000-0002-7377-2955
Gerhard KrönkeDepartment of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen and Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Christoph AlexiouDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Rainer TietzeDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Universitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DETechnische Universität Ilmenau · DE

Funding

DGF (CI 162/2-3)Dr. Pfleger Stiftung, BambergThüringer Innovationszentrum für Medizintechnik-Lösungen ThIMEDOP; FKZ IZN 2018 0002
6 · The paper itself

Abstract

Hydroxyapatite- or calcium phosphate-coated iron oxide nanoparticles have a high potential for use in many biomedical applications. In this study, a co-precipitation method for the synthesis of hydroxyapatite-coated nanoparticles (SPION

Indexed as

AnimalsBone Marrow CellsCells, CulturedDurapatiteHumansInterleukin-6Jurkat CellsLipopolysaccharidesMacrophagesMagnetic Iron Oxide NanoparticlesMiceMice, Inbred C57BLTHP-1 CellsTumor Necrosis Factor-alphaDurapatiteInterleukin-6LipopolysaccharidesTumor Necrosis Factor-alphacytokine releasedexamethasonehydroxyapatiteiron oxide nanoparticleslipopolysaccharidesmacrophages

Identifiers

PMID33923700
PMCPMC8072956
OpenAlexW3156579665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.