Evidence map›Paper›PMID 33923667›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation of Uterine Fibroids-Efficiency Assessment with the Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging and the Potential Role of the Administration of Uterotonic Drugs.

Tomasz Łoziński, Michał Ciebiera, Elżbieta Łuczyńska, Justyna Filipowska, Artur Czekierdowski

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tomasz ŁozińskiDepartment of Obstetrics and Gynecology, Pro-Familia Hospital, 35-302 Rzeszow, Poland.
Michał CiebieraSecond Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, 01-809 Warsaw, Poland.ORCID 0000-0001-5780-5983
Elżbieta ŁuczyńskaDepartment of Radiology and Nuclear Medicine, Institute of Medical Sciences, Faculty of Medicine, University of Rzeszow, 35-310 Rzeszow, Poland.ORCID 0000-0003-4872-7172
Justyna FilipowskaDepartment of Radiology and Nuclear Medicine, Institute of Medical Sciences, Faculty of Medicine, University of Rzeszow, 35-310 Rzeszow, Poland.
Artur CzekierdowskiDepartment of Gynecological Oncology and Gynecology, Medical University of Lublin, 20-081 Lublin, Poland.
University of Rzeszów · PLMedical University of Lublin · PLPostgraduate School of Molecular Medicine · PL

Funding

European Regional Development Fund Programme: Intelligent Development Operational Pro-gram (2014-2020): 'Development and implementation of a noninvasive, personalized thermo-ablation procedure in the treatment of specific types of neoplasms' POIR.01.01.01-00-0019/15-00European Regional Development Fund Programme: Operational Programme 'Innovative economy' (2007-2013): 'Establishing a Research and Development Center of noninvasive therapeutic methods'. POIG.04.05.02-00-075/12-00
6 · The paper itself

Abstract

objectiveThe assessment of the usefulness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) when qualifying patients with uterine fibroids (UFs) for magnetic resonance-guided high-intensity ultrasound (MR-HIFU). MATERIAL AND

methodsThis retrospective, single center study included 283 women who underwent DCE-MRI and were treated with MR-HIFU. The patients were divided according to non-perfused volume (NPV) as well as by the type of curve for patients with a washout curve in the DCE-MRI study and patients without a washout curve. The studied women were assessed in three groups according to the type of uterotonics administered. Group A (57 patients) received one dose of misoprostol/diclofenac transvaginally and group B (71 patients) received oxytocin intravenously prior to the MR-HIFU procedure. The remaining 155 women (group C) were treated with the traditional non-drug enhanced MR-HIFU procedure.

resultsThe average NPV value was higher in no washout group, and depended on the uterotonics used.

conclusionsWe demonstrated a correlation between dynamic contrast enhancement curve types and the therapeutic efficacy of MR-HIFU. Our results suggest that DCE-MRI has the potential to assess treatment outcomes among patients with UFs, and patients with UFs that present with a washout curve may benefit from the use of uterotonic drugs. More studies are required to draw final conclusions.

Indexed as

diffusion-weighted magnetic resonance imaging (DWI)dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)leiomyomamagnetic resonance-guided high-intensity focused ultrasound (MR-HIFU)uterine fibroid

Identifiers

PMID33923667
PMCPMC8072686
OpenAlexW3155511570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.