Evidence map›Paper›PMID 33923625›Full record

ArticleInternational journal of molecular sciences2021

Role of α2-Adrenoceptor Subtypes in Suppression of L-Type Ca

Edward V Evdokimovskii, Ryounghoon Jeon, Sungjo Park, Oleg Y Pimenov, Alexey E Alekseev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. αBulletin of experimental biology and medicine · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Edward V EvdokimovskiiInstitute of Theoretical and Experimental Biophysics, Russian Academy of Science, Institutskaya 3, 142290 Pushchino, Russia.
Ryounghoon JeonDepartment of Cardiovascular Medicine, Center for Regenerative Medicine, Mayo Clinic, Stabile 5, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.ORCID 0000-0003-3174-1197
Sungjo ParkDepartment of Cardiovascular Medicine, Center for Regenerative Medicine, Mayo Clinic, Stabile 5, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA.ORCID 0000-0003-1210-7000
Oleg Y PimenovInstitute of Theoretical and Experimental Biophysics, Russian Academy of Science, Institutskaya 3, 142290 Pushchino, Russia.
Alexey E AlekseevInstitute of Theoretical and Experimental Biophysics, Russian Academy of Science, Institutskaya 3, 142290 Pushchino, Russia.
Mayo Clinic · USInstitute of Theoretical and Experimental Biophysics · RU

Funding

Russian Science Foundation 18-15-00198
6 · The paper itself

Abstract

Sarcolemmal α2 adrenoceptors (α2-AR), represented by α2A, α2B and α2C isoforms, can safeguard cardiac muscle under sympathoadrenergic surge by governing Ca

Indexed as

Action PotentialsAnimalsCalcium Channels, L-TypeCells, CulturedHeart VentriclesMiceMice, Inbred C57BLMyocytes, CardiacProtein IsoformsReceptors, Adrenergic, alpha-2Adra2a protein, mouseCalcium Channels, L-TypeProtein IsoformsReceptors, Adrenergic, alpha-2ARC 239BRL 44408cell signalingG-protein coupled receptorsguanabenzJP 1302left ventricle

Identifiers

PMID33923625
PMCPMC8072751
OpenAlexW3156950148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.