Evidence map›Paper›PMID 33923467›Full record

ArticleMolecules (Basel, Switzerland)2021

Multiple Roles of Black Raspberry Anthocyanins Protecting against Alcoholic Liver Disease.

Ting Xiao, Zhonghua Luo, Zhenghong Guo, Xude Wang, Meng Ding, Wei Wang, Xiangchun Shen, Yuqing Zhao

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Berries vs. Disease: Revenge of the Phytochemicals.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Probiotics-FermentedInternational journal of molecular sciences · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Rhoifolin Alleviates Alcoholic Liver DiseaseFrontiers in pharmacology · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ting XiaoThe State Key Laboratory of Functions and Applications of Medicinal Plants, The Department of Pharmaceutic Preparation of Chinse Medicine, The High Educational Key Laboratory of Guizhou Province for Natural Medicianl Pharmacology and Druggability, School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550025, China.ORCID 0000-0002-3489-4124
Zhonghua LuoSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zhenghong GuoSchool of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.
Xude WangSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Meng DingSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wei WangSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiangchun ShenThe State Key Laboratory of Functions and Applications of Medicinal Plants, The Department of Pharmaceutic Preparation of Chinse Medicine, The High Educational Key Laboratory of Guizhou Province for Natural Medicianl Pharmacology and Druggability, School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550025, China.
Yuqing ZhaoSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shenyang Pharmaceutical University · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the protective effect of black raspberry anthocyanins (BRAs) against acute and subacute alcoholic liver disease (ALD). Network analysis and docking study were carried out to understand the potential mechanism. Thereafter, the serum biochemical parameters and liver indexes were measured, the histopathological changes of the liver were analyzed in vivo. The results showed that all tested parameters were ameliorated after the administration of BRAs with alcohol. Meanwhile, there was increased protein expression of NF-κB and TGF-β in extracted livers, which was associated with hepatitis and hepatic fibrosis. Furthermore, BRAs and cyanidin-

Indexed as

AnthocyaninsAntioxidantsApoptosisCaspase 3Caspase 9Cytochromes cHep G2 CellsHumansLiver Diseases, AlcoholicSpectroscopy, Fourier Transform InfraredAnthocyaninsAntioxidantsCaspase 3Caspase 9Cytochromes calcoholic liver injuryanthocyaninsantioxidantapoptosisblack raspberry

Identifiers

PMID33923467
PMCPMC8073606
OpenAlexW3154352451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.