Evidence map›Paper›PMID 33923425›Full record

ReviewBioengineering (Basel, Switzerland)2021

Protein-Based 3D Biofabrication of Biomaterials.

Mahta Mirzaei, Oseweuba Valentine Okoro, Lei Nie, Denise Freitas Siqueira Petri, Amin Shavandi

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  5. Frontiers in 3D printing for biobased food packaging.Food science and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Mahta MirzaeiBioMatter Unit, École polytechnique de Bruxelles, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium.
Oseweuba Valentine OkoroBioMatter Unit, École polytechnique de Bruxelles, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium.ORCID 0000-0002-9291-0225
Lei NieCollege of Life Sciences, Xinyang Normal University, Xinyang 464000, China.ORCID 0000-0002-6175-5883
Denise Freitas Siqueira PetriFundamental Chemistry Department, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.ORCID 0000-0003-4814-8357
Amin ShavandiBioMatter Unit, École polytechnique de Bruxelles, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium.ORCID 0000-0002-0188-3090
Université Libre de Bruxelles · BEUniversidade de São Paulo · BRXinyang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein/peptide-based hydrogel biomaterial inks with the ability to incorporate various cells and mimic the extracellular matrix's function are promising candidates for 3D printing and biomaterials engineering. This is because proteins contain multiple functional groups as reactive sites for enzymatic, chemical modification or physical gelation or cross-linking, which is essential for the filament formation and printing processes in general. The primary mechanism in the protein gelation process is the unfolding of its native structure and its aggregation into a gel network. This network is then stabilized through both noncovalent and covalent cross-link. Diverse proteins and polypeptides can be obtained from humans, animals, or plants or can be synthetically engineered. In this review, we describe the major proteins that have been used for 3D printing, highlight their physicochemical properties in relation to 3D printing and their various tissue engineering application are discussed.

Indexed as

3D printingpeptidesprotein-based hydrogels

Identifiers

PMID33923425
PMCPMC8073780
OpenAlexW3155745243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.