Evidence map›Paper›PMID 33923359›Full record

ReviewMolecules (Basel, Switzerland)2021

The Role of Resveratrol in Human Male Fertility.

Laura M Mongioì, Sarah Perelli, Rosita A Condorelli, Federica Barbagallo, Andrea Crafa, Rossella Cannarella, Sandro La Vignera, Aldo E Calogero

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Resveratrol and Female Fertility: A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  2. Nutritional modulation of male fertility: a molecular-focused scoping review.Journal of health, population, and nutrition · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. The aryl hydrocarbon receptor: a new frontier in male reproductive system.Reproductive biology and endocrinology : RB&E · 2025
    Review
  11. Article
  12. Review
  13. Assessing the Efficacy of Acanthoic Acid Isolated fromCurrent issues in molecular biology · 2024
    Article
  14. Review
  15. Article
  16. How Food Choices Impact on Male Fertility.Current nutrition reports · 2023
    Review
  17. Review
  18. Natural products for treatment of premature ovarian failure: a narrative review.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Laura M MongioìDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.ORCID 0000-0003-2341-0996
Sarah PerelliDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.
Rosita A CondorelliDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.ORCID 0000-0002-5217-9343
Federica BarbagalloDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.
Andrea CrafaDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.
Rossella CannarellaDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.ORCID 0000-0003-4599-8487
Sandro La VigneraDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.ORCID 0000-0002-7113-2372
Aldo E CalogeroDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.ORCID 0000-0001-6950-335X
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol (RSV) (3,4',5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.

Indexed as

ArachisDiet, MediterraneanFertilityFertility Agents, MaleFruitHumansMalePolyphenolsResveratrolSpermatozoaVitisWineFertility Agents, MalePolyphenolsResveratrolcryopreservationhuman male fertilityresveratrolsperm parameters

Identifiers

PMID33923359
PMCPMC8123193
OpenAlexW3157377117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.