Evidence map›Paper›PMID 33923332›Full record

ArticleJournal of personalized medicine2021

Predicting in-Hospital Mortality of Patients with COVID-19 Using Machine Learning Techniques.

Fabiana Tezza, Giulia Lorenzoni, Danila Azzolina, Sofia Barbar, Lucia Anna Carmela Leone, Dario Gregori

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Prediction of COVID-19 Patients' Survival by Deep Learning Approaches.Medical journal of the Islamic Republic of Iran · 2022
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  20. Computational Intelligence-Based Model for Mortality Rate Prediction in COVID-19 Patients.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabiana TezzaGeriatric Unit, Ospedali Riuniti di Padova Sud, AULSS 6 Euganea, 35043 Monselice, Italy.ORCID 0000-0002-3897-5140
Giulia LorenzoniUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-1771-4686
Danila AzzolinaUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-8185-5742
Sofia BarbarInternal Medicine Unit, Cittadella Hospital, AULSS 6 Euganea, 35013 Cittadella, Italy.
Lucia Anna Carmela LeoneInternal Medicine Unit, Ospedali Riuniti Padova Sud, AULSS 6 Euganea, 35043 Monselice, Italy.
Dario GregoriUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-7906-0580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work aims to identify the predictors of COVID-19 in-hospital mortality testing a set of Machine Learning Techniques (MLTs), comparing their ability to predict the outcome of interest. The model with the best performance will be used to identify in-hospital mortality predictors and to build an in-hospital mortality prediction tool. The study involved patients with COVID-19, proved by PCR test, admitted to the "Ospedali Riuniti Padova Sud" COVID-19 referral center in the Veneto region, Italy. The algorithms considered were the Recursive Partition Tree (RPART), the Support Vector Machine (SVM), the Gradient Boosting Machine (GBM), and Random Forest. The resampled performances were reported for each MLT, considering the sensitivity, specificity, and the Receiving Operative Characteristic (ROC) curve measures. The study enrolled 341 patients. The median age was 74 years, and the male gender was the most prevalent. The Random Forest algorithm outperformed the other MLTs in predicting in-hospital mortality, with a ROC of 0.84 (95% C.I. 0.78-0.9). Age, together with vital signs (oxygen saturation and the quick SOFA) and lab parameters (creatinine, AST, lymphocytes, platelets, and hemoglobin), were found to be the strongest predictors of in-hospital mortality. The present work provides insights for the prediction of in-hospital mortality of COVID-19 patients using a machine-learning algorithm.

Indexed as

COVID-19in-hospital mortalityItalymachine learning techniquesoutcome prediction

Identifiers

PMID33923332
PMCPMC8147079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.