Evidence map›Paper›PMID 33923324›Full record

ArticleCells2021

Transcriptome Analysis of Hypoxic Lymphatic Endothelial Cells Indicates Their Potential to Contribute to Extracellular Matrix Rearrangement.

Jürgen Becker, Sonja Schwoch, Christina Zelent, Maren Sitte, Gabriela Salinas, Jörg Wilting

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Study on the Correlation between the Levels of HtrA3 and TGF-Journal of healthcare engineering · 2022
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jürgen BeckerDepartment of Anatomy and Cell Biology, University Medical School Göttingen, 37075 Göttingen, Germany.
Sonja SchwochDepartment of Anatomy and Cell Biology, University Medical School Göttingen, 37075 Göttingen, Germany.
Christina ZelentDepartment of Anatomy and Cell Biology, University Medical School Göttingen, 37075 Göttingen, Germany.
Maren SitteNGS-Integrative Genomics Core Unit (NIG), Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany.
Gabriela SalinasNGS-Integrative Genomics Core Unit (NIG), Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany.
Jörg WiltingDepartment of Anatomy and Cell Biology, University Medical School Göttingen, 37075 Göttingen, Germany.ORCID 0000-0001-8337-2296
Universitätsmedizin Göttingen · DE

Funding

Verein zur Förderung der Lymphologie e.V., Hinterzarten, Germany JW_2019
6 · The paper itself

Abstract

Lymphedema (LE) affects millions of people worldwide. It is a chronic progressive disease with massive development of fibrosclerosis when untreated. There is no pharmacological treatment of lymphedema. The disease is associated with swelling of the interstitium of the affected organ, mostly arm or leg, impressive development of adipose tissue, fibrosis and sclerosis with accumulation of huge amounts of collagen, and

Indexed as

TranscriptomeCells, CulturedEndothelial CellsExtracellular MatrixExtracellular Matrix ProteinsGene Expression RegulationHumansHypoxiaExtracellular Matrix ProteinsADAMTS15ceruloplasmincollagenelastinextracellular matrixfibrillogenesisfibromodulinfibulin 5GLUT3hyaluronanhypoxiaTGFΒ

Identifiers

PMID33923324
PMCPMC8145299
OpenAlexW3157631121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.