ArticleInternational journal of environmental research and public health2021
A Case of Silicone and Sarcoid Granulomas in a Patient with "Highly Cohesive" Silicone Breast Implants: A Histopathologic and Laser Raman Microprobe Analysis.
Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- Cardiac Granulomatous Disease Following Silicone Breast Augmentation: A Rare Cause of Symptomatic Sinus Node Dysfunction.JACC. Case reports · 2025Article
- Presentation and Management of Silicone Lymphadenopathy: A Single Institutional Retrospective Cohort Study.Aesthetic plastic surgery · 2025Article
- The Role of Positron Emission Tomography Imaging in Breast Implant Illness.Plastic and reconstructive surgery. Global open · 2025Article
- Extracapsular breast implant rupture with silicone migration and lymphadenopathy following a breast augmentation - A case report.Case reports in plastic surgery & hand surgery · 2025Article
- Ultrasound versus MRI for evaluation of silicone leakage from silicone breast implants.Heliyon · 2024Article
- Silicone Migration from Intact Saline Breast Implants.Plastic and reconstructive surgery. Global open · 2024Article
- Breast implant iatrogenics: challenging the safety narrative.Frontiers in global women's health · 2024Article
- Assessment of Silicone Particle Migration Among Women Undergoing Removal or Revision of Silicone Breast Implants in the Netherlands.JAMA network open · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foreign body giant cell (FBGC) reaction to silicone material in the lymph nodes of patients with silicone breast implants has been documented in the literature, with a number of case reports dating back to 1978. Many of these case reports describe histologic features of silicone lymphadenopathy in regional lymph nodes from patients with multiple sets of different types of implants, including single lumen smooth surface gel, single lumen textured surface gel, single lumen with polyethylene terephthalate patch, single lumen with polyurethane coating, and double lumen smooth surface. Only one other case report described a patient with highly-cohesive breast implants and silicone granulomas of the skin. In this article, we describe a patient with a clinical presentation of systemic sarcoidosis following highly cohesive breast implant placement. Histopathologic analysis and Confocal Laser Raman Microprobe (CLRM) examination were used to confirm the presence of silicone in the axillary lymph node and capsular tissues. This is the first report where chemical spectroscopic mapping has been used to establish and identify the coexistence of Schaumann bodies, consisting of calcium oxalate and calcium phosphate minerals, together with silicone implant material.
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Registered trials
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