Evidence map›Paper›PMID 33923202›Full record

ReviewInternational journal of molecular sciences2021

Nasal Epithelial Cell-Based Models for Individualized Study in Cystic Fibrosis.

Duncan E Keegan, John J Brewington

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine.American journal of respiratory cell and molecular biology · 2024
    Article
  5. The ageing of people living with cystic fibrosis: what to expect now?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  6. Cystic fibrosis.Nature reviews. Disease primers · 2024
    Review
  7. Article
  8. Review
  9. Biobanked tracheal basal cells retain the capacity to differentiate.Laryngoscope investigative otolaryngology · 2022
    Article
  10. Review
  11. Article
  12. Assays of CFTR Function In Vitro, Ex Vivo and In Vivo.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Duncan E KeeganDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center (CCHMC), 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
John J BrewingtonDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center (CCHMC), 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
University of Cincinnati Medical Center · US

Funding

Personalized Model Systems to Predict and Investigate CFTR Drug Response in CFK08HL144825 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BREWINGTON, JOHN JOSEPH · 2019 to 2023
$818k
Cystic Fibrosis Foundation BREWIN20A0-KBCystic Fibrosis Foundation BREWIN20Y2-OUTCystic Fibrosis Foundation KEEGAN19B0NHLBI NIH HHS HL144825-01A1NHLBI NIH HHS K08 HL144825
6 · The paper itself

Abstract

The emergence of highly effective CFTR modulator therapy has led to significant improvements in health care for most patients with cystic fibrosis (CF). For some, however, these therapies remain inaccessible due to the rarity of their individual

Indexed as

Models, BiologicalPrecision MedicineAnimalsCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsHumansNasal MucosaCystic Fibrosis Transmembrane Conductance RegulatorCFTRcystic fibrosisnasal cellpersonalized medicinetheratyping

Identifiers

PMID33923202
PMCPMC8123210
OpenAlexW3159075303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.