ArticleBiomedicines2021
Association between Vitamin D Deficiency and High Serum Levels of Small Dense LDL in Middle-Aged Adults.
Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Associations between serum vitamin DBMC endocrine disorders · 2022Trial
- Association between serum vitamin D levels and atherogenic lipid subfractions: insights from NMR-based lipid profiling in a large adult population.Scientific reports · 2026Article
- Associations between vitamin D insufficiency, health beliefs, and quality of life in metabolic syndrome: A northeastern Taiwanese community study.Asia Pacific journal of clinical nutrition · 2026Article
- Predictors of vitamin D deficiency and quality of life in obese patients with obstructive sleep apnea.Scientific reports · 2026Article
- Factors associated with the serum 25-hydroxyvitamin D levels in adults.BMC nutrition · 2025Article
- The prevalence of vitamin D deficiency and its association to modifiable risk factors of cardiovascular disease among apparently healthy adults in Central Kerala.Journal of family medicine and primary care · 2025Article
- Nutritional Support of Chronic Obstructive Pulmonary Disease.Nutrients · 2025Review
- The Sunshine Paradox: Unraveling Risk Factors for Low Vitamin D Status Among Non-Pregnant Women in Lebanon.Nutrients · 2025Article
- Comparison between the protective effect of the orally administered atorvastatin and safflower (Frontiers in pharmacology · 2025Article
- The Impact of Atorvastatin Treatment on the Distribution of Low-Density Lipoprotein Subfractions and the Level of Vitamin D in Patients After Acute Myocardial Infarction: Preliminary Findings.International journal of molecular sciences · 2024Article
- Relationship between Vitamin D Insufficiency, Lipid Profile and Atherogenic Indices in Healthy Women Aged 18-50 Years.European journal of investigation in health, psychology and education · 2024Article
- Prevalence and patterns of vitamin D deficiency and its role in cognitive functioning in a cohort from South India.Scientific reports · 2024Article
- The Importance of Preventing Vitamin D Deficiency.Journal of atherosclerosis and thrombosis · 2024Article
- Association Between Adequate Serum 25(OH)D Levels and Atherogenic Dyslipidemia in Young Adults.Journal of atherosclerosis and thrombosis · 2024Article
- Review
- Article
- Effect of Nutrition Education on Health Science University Students to Improve Cardiometabolic Profile and Inflammatory Status.Nutrients · 2023Article
- Higher Dietary Vitamin D Intake Influences the Lipid Profile and hs-CRP Concentrations: Cross-Sectional Assessment Based on The National Health and Nutrition Examination Survey.Life (Basel, Switzerland) · 2023Article
- Vitamin D Status and Potential Therapeutic Options in Critically Ill Patients: A Narrative Review of the Clinical Evidence.Diagnostics (Basel, Switzerland) · 2022Review
- The correlation of 25-hydroxyvitamin D with BMI and lipid profile: A retrospective cohort study of Syrian patients.Annals of medicine and surgery (2012) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Recent studies suggested a potential link between vitamin D deficiency and cardiovascular risk factors, including dyslipidemia. This study aimed to investigate the association between serum 25(OH)D levels and atherogenic lipid profiles, specifically, that of small dense low-density lipoprotein-cholesterol (sdLDL-C). From 2009 to 2011, a total of 715 individuals aged 35-65 without evident cardiovascular disease (CVD) were enrolled. Their levels of serum 25(OH)D and lipid profiles were measured. Vitamin D deficiency was found to be more common in females, smokers, alcohol drinkers, individuals at a younger age, and those who do not exercise regularly. The analysis of lipid profiles revealed that high sdLDL-C levels were associated with low serum vitamin D levels and were more common among cigarette smokers; alcohol drinkers; individuals with hypertension; individuals with high BMI; and those with high levels of fasting blood glucose, triglycerides, LDL-C, and VLDL-C. The use of multivariate logistic regression verified a strong negative correlation between low vitamin D status (serum 25(OH)D < 15 ng/mL) and the three identified biomarkers of atherogenic dyslipidemia: high serum levels of sdLDL-C, triglycerides, and VLDL-C. This study provides strong evidence that vitamin D deficiency is associated with atherogenic dyslipidemia, and in particular, high sdLDL-C levels in middle-aged adults without CVD.
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Registered trials
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