Evidence map›Paper›PMID 33923166›Full record

ArticleCells2021

KLF5 Is Activated by Gene Amplification in Gastric Cancer and Is Essential for Gastric Cell Proliferation.

Wei Chen, Jian Zhang, Huafeng Fu, Xun Hou, Qiao Su, Yulong He, Dongjie Yang

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  2. Cells · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wei ChenCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Jian ZhangCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.ORCID 0000-0001-8870-515X
Huafeng FuCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Xun HouCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Qiao SuAnimal Experiment Center, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Yulong HeCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Dongjie YangCenter for Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
Sun Yat-sen University · CN

Funding

National Natural Science Foundation of China 81672333Sun Yat-Sen University Clinical Research 5010 Program 2010006The Science & Technology Planning Project of Guangdong Province 2017A030303015
6 · The paper itself

Abstract

Gastric cancer is the third leading cause of cancer death worldwide. In this study, we tried to clarify the function of

Indexed as

Cell ProliferationDNA Copy Number VariationsGene AmplificationGene Expression Regulation, NeoplasticBiomarkers, TumorCase-Control StudiesCell DifferentiationFemaleFollow-Up StudiesHumansKruppel-Like Transcription FactorsMaleMiddle AgedMutationPrognosisStomach NeoplasmsBiomarkers, TumorKLF5 protein, humanKruppel-Like Transcription Factorscopy number variationgastric cancerKLF5TCGA

Identifiers

PMID33923166
PMCPMC8152363
OpenAlexW3159563714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.