Evidence map›Paper›PMID 33923123›Full record

ArticleChildren (Basel, Switzerland)2021

Sustained Surface ICAM-1 Expression and Transient PDGF-B Production by Phorbol Myristate Acetate-Activated THP-1 Cells Harboring Blau Syndrome-Associated

Mizuho Nishiyama, Hong-Jin Li, Ikuo Okafuji, Akihiko Fujisawa, Mizue Ehara, Naotomo Kambe, Fukumi Furukawa, Nobuo Kanazawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Mizuho NishiyamaDepartment of Dermatology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Hong-Jin LiDepartment of Dermatology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Ikuo OkafujiDepartment of Pediatrics, Kobe City Medical Center General Hospital, Kobe 650-0047, Japan.
Akihiko FujisawaDepartment of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Mizue EharaDepartment of Dermatology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Naotomo KambeDepartment of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.
Fukumi FurukawaDepartment of Dermatology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Nobuo KanazawaDepartment of Dermatology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.ORCID 0000-0003-3000-9711
Wakayama Medical University · JPChiba University · JPHyogo Medical University · JPKobe City Medical Center General Hospital · JPKyoto University · JP

Funding

Japan Society for the Promotion of Science 19K08798Ministry of Health, Labour and Welfare 19K08798
6 · The paper itself

Abstract

objectivesBlau syndrome is a distinct class of autoinflammatory syndrome presenting with early-onset systemic granulomatosis. Blau syndrome-causing

methodsBlau syndrome-causing

resultsAlthough the production of proinflammatory cytokines was not altered without stimulation, mutant

conclusionsSustained surface ICAM-1 expression and transient PDGF-B production by newly differentiating macrophages harboring mutant

Indexed as

Blau syndromeICAM-1NOD2 mutationPDGF-B

Identifiers

PMID33923123
PMCPMC8145400
OpenAlexW3157034972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.