ArticleJournal of clinical medicine2021
A New Experimental Porcine Model of Venous Thromboembolism.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Unveiling the molecular impact of pulmonary embolism on the right ventricle: a multi-layer transcriptomic study in a porcine model.Molecular and cellular biochemistry · 2026Article
- In Vivo Porcine Model of Acute Iliocaval Deep Vein Thrombosis.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2025Article
- Characterization of spreading depolarizations in swine following superior sagittal sinus occlusion: a novel gyrencephalic model study.Thrombosis journal · 2025Article
- Distribution and Chemistry of Phoenixin-14, a Newly Discovered Sensory Transmission Molecule in Porcine Afferent Neurons.International journal of molecular sciences · 2023Article
- Thrombosis Models: An Overview of Common In Vivo and In Vitro Models of Thrombosis.International journal of molecular sciences · 2023Review
- Pulmonary artery embolism: comprehensive transcriptomic analysis in understanding the pathogenic mechanisms of the disease.BMC genomics · 2023Article
- Article
- Assessment of knowledge and practice of venous thromboembolism (VTE) prophylaxis after cesarean section among gynecologists and obstetricians in Al-Najaf hospitals.Journal of medicine and lifeObservational
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a severe disease affecting the human venous system, accompanied by high morbidity and mortality rates. The aim of the study was to establish a new porcine VTE model based on the formation of the thrombus in vivo. The study was performed on 10 castrated male pigs: thrombus was formed in each closed femoral vein and then successfully released from the right femoral vein into the circulation of animals. In six pigs PE was confirmed via both computed tomography pulmonary angiography and an autopsy. Our research presents a novel experimental porcine model of VTE that involves inducing DVT and PE in the same animal in vivo, making it suitable for advanced clinical research and testing of future therapies.
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Registered trials
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