Evidence map›Paper›PMID 33923004›Full record

ArticleMolecules (Basel, Switzerland)2021

Multi-Target Strategy to Uncover Unexpected Compounds in Rinse-Off and Leave-On Cosmetics.

Maria Celeiro, Laura Rubio, Carmen Garcia-Jares, Marta Lores

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria CeleiroDepartment of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, CRETUS Institute, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.ORCID 0000-0002-3212-5743
Laura RubioDepartment of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, CRETUS Institute, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.ORCID 0000-0002-2100-1550
Carmen Garcia-JaresDepartment of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, CRETUS Institute, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.ORCID 0000-0002-2233-6512
Marta LoresDepartment of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, CRETUS Institute, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain.ORCID 0000-0001-7683-8342

Funding

Xunta de Galicia ED431 2020/06Xunta de Galicia ED431E 2018/01Xunta de Galicia ED481A-2018/227
6 · The paper itself

Abstract

The wide range and complexity of cosmetic formulations currently available on the market poses a challenge from an analytical point of view. In addition, during cosmetics manufacture, impurities coming from raw materials or formed by reaction of different organic compounds present in the formulation may be present. Their identification is mandatory to assure product quality and consumer health. In this work, micro-matrix solid-phase dispersion (μMSPD) is proposed as a multi-target sample preparation strategy to analyze a wide number of unexpected families of compounds including polycyclic aromatic hydrocarbons (PAHs), pesticides, plasticizers, nitrosamines, alkylphenols (APs), and alkylphenol ethoxylates (APEOs). Analytical determination was performed by gas chromatography-mass spectrometry (GC-MS) for the determination of 51 target compounds in a single run, whereas liquid chromatography tandem mass spectrometry (LC-MS/MS) was employed for the analysis of six APs and APEOs. Both methodologies were successfully validated in terms of linearity, accuracy, and precision in leave-on and rinse-off cosmetics. Limits of detection (LODs) were calculated in the low ng g

Indexed as

CosmeticsGas Chromatography-Mass SpectrometryHumansLimit of DetectionNitrosaminesPesticidesPolycyclic Aromatic HydrocarbonsSolid Phase ExtractionCosmeticsNitrosaminesPesticidesPolycyclic Aromatic Hydrocarbonsalkylphenol ethoxylatesbanned compoundscosmetics analysisgas chromatographyliquid chromatographymass spectrometryminiaturized sample preparationnitrosaminespesticidespolycyclic aromatic hydrocarbons

Identifiers

PMID33923004
PMCPMC8123312

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.