Evidence map›Paper›PMID 33922927›Full record

ArticleMolecules (Basel, Switzerland)2021

Piroxicam Loading onto Mesoporous Silicas by Supercritical CO

Marta Gallo, Luca Serpella, Federica Leone, Luigi Manna, Mauro Banchero, Silvia Ronchetti, Barbara Onida

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Nanoconfinement-Enhanced COMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Silica-Cyclodextrin Hybrid Materials: Two Possible Synthesis Processes.International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marta GalloDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0002-0001-052X
Luca SerpellaDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.
Federica LeoneDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0003-0905-8535
Luigi MannaDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0002-1997-437X
Mauro BancheroDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0003-1508-3921
Silvia RonchettiDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0002-5744-8813
Barbara OnidaDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi, 24, 10129 Torino, Italy.ORCID 0000-0002-1928-3579
Politecnico di Torino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piroxicam (PRX) is a commonly prescribed nonsteroidal anti-inflammatory drug. Its efficacy, however, is partially limited by its low water solubility. In recent years, different studies have tackled this problem and have suggested delivering PRX through solid dispersions. All these strategies, however, involve the use of potentially harmful solvents for the loading procedure. Since piroxicam is soluble in supercritical CO

Indexed as

Anti-Inflammatory Agents, Non-SteroidalEthanolHumansInflammationPiroxicamSilicon DioxideSolubilityWaterAnti-Inflammatory Agents, Non-SteroidalEthanolPiroxicamSilicon DioxideWaterGrace Syloid® XDPincorporationmesoporous silicaNSAIDpiroxicamSBA-15solubilitysupercritical CO2

Identifiers

PMID33922927
PMCPMC8123285
OpenAlexW3158845038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.