Evidence map›Paper›PMID 33922829›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Can Alveolar-Arterial Difference and Lung Ultrasound Help the Clinical Decision Making in Patients with COVID-19?

Gianmarco Secco, Francesco Salinaro, Carlo Bellazzi, Marco La Salvia, Marzia Delorenzo, Caterina Zattera, Bruno Barcella, Flavia Resta, Giulia Vezzoni, Marco Bonzano and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Lung Ultrasound Score in COVID-19 Patients Correlates with POThe western journal of emergency medicine · 2024
    Pooled it
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gianmarco SeccoEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0001-9476-6645
Francesco SalinaroEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Carlo BellazziEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0002-4324-3921
Marco La SalviaDepartment of Electrical, Computer and Biomedical Engineering, University of Pavia, 27100 Pavia, Italy.
Marzia DelorenzoEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Caterina ZatteraEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Bruno BarcellaEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0002-9326-2602
Flavia RestaEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Giulia VezzoniEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Marco BonzanoEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Giovanni CappaEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Raffaele BrunoInfectious Disease Unit, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0002-0235-9207
Ivo CasagrandaAcademy of Emergency Medicine and Care (AcEMC), 27100 Pavia, Italy.
Stefano PerliniEmergency Medicine Unit and Emergency Medicine Postgraduate Training Program, Department of Internal Medicine, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0002-0320-8574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is an emerging infectious disease, that is heavily challenging health systems worldwide. Admission Arterial Blood Gas (ABG) and Lung Ultrasound (LUS) can be of great help in clinical decision making, especially during the current pandemic and the consequent overcrowding of the Emergency Department (ED). The aim of the study was to demonstrate the capability of alveolar-to-arterial oxygen difference (AaDO

methodsA cohort of 223 swab-confirmed COVID-19 patients underwent clinical evaluation, blood tests, ABG and LUS in the ED. LUS score was derived from 12 ultrasound lung windows. AaDO

resultsA close relationship between AaDO

conclusionsLUS and AaDO

Indexed as

arterial-alveolar differenceCOVID-19emergency departmentlung injurylung ultrasoundP/Fpneumonia

Identifiers

PMID33922829
PMCPMC8145474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.