Evidence map›Paper›PMID 33922668›Full record

ArticleLife (Basel, Switzerland)2021

Effects of Hemispheric Stroke Localization on the Reorganization of Arm Movements within Different Mechanical Environments.

Laura Pellegrino, Martina Coscia, Camilla Pierella, Psiche Giannoni, Amel Cherif, Maddalena Mugnosso, Lucio Marinelli, Maura Casadio

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Roles of Handedness and Hemispheric Lateralization: Implications for Rehabilitation of the Central and Peripheral Nervous Systems: A Rapid Review.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Laura PellegrinoDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.
Martina CosciaBertarelli Foundation Chair in Translational Neuroengineering, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0002-0280-3486
Camilla PierellaDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0002-8108-9363
Psiche GiannoniDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.
Amel CherifDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.
Maddalena MugnossoDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.
Lucio MarinelliDepartment of Neurosciences, Rehabilitation, Ophthalmology, Genetics, and Maternal and Children's Sciences (DINOGMI), University of Genova, 16126 Genoa, Italy.ORCID 0000-0003-0620-7654
Maura CasadioDepartment Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, 16126 Genoa, Italy.ORCID 0000-0003-2338-8995
University of Genoa · ITItalian Institute of Technology · ITOspedale Policlinico San Martino · ITWyss Center for Bio and Neuroengineering · CH

Funding

FP7 People: Marie-Curie Actions FP7-PEOPLE-2012-CIG-334201 (REMAKE)Ministry of Science and Technology, Israel Joint Israel-Italy lab in Biorobotics Artificial somatosensation for humans and humanoidsResearch projects of national interest PRIN-2015HFWRYY
6 · The paper itself

Abstract

This study investigated how stroke's hemispheric localization affects motor performance, spinal maps and muscle synergies while performing planar reaching with and without assistive or resistive forces. A lesion of the right hemisphere affected performance, reducing average speed and smoothness and augmenting lateral deviation in both arms. Instead, a lesion of the left hemisphere affected the aiming error, impairing the feedforward control of the ipsilesional arm. The structure of the muscle synergies had alterations dependent on the lesion side in both arms. The applied force fields reduced the differences in performance and in muscle activations between arms and among populations. These results support the hypotheses of hemispheric specialization in movement control and identify potential significant biomarkers for the design of more effective and personalized rehabilitation protocols.

Indexed as

muscle synergiesrobot-based assessmentspinal mapsstroke subjectsupper limb

Identifiers

PMID33922668
PMCPMC8145329
OpenAlexW3157580622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.