Evidence map›Paper›PMID 33922622›Full record

ReviewAnimals : an open access journal from MDPI2021

Strategies for Highly Efficient Rabbit Sperm Cryopreservation.

Kazutoshi Nishijima, Shuji Kitajima, Fumikazu Matsuhisa, Manabu Niimi, Chen-Chi Wang, Jianglin Fan

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Rabbit Sperm Cryopreservation.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Kazutoshi NishijimaCenter for Animal Resources and Collaborative Study, National Institutes of Natural Sciences, 38 Nishigonaka, Myodaiji, Okazaki 444-8585, Japan.
Shuji KitajimaAnalytical Research Center for Experimental Sciences, Division of Biological Resources and Development, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.ORCID 0000-0002-6239-2682
Fumikazu MatsuhisaAnalytical Research Center for Experimental Sciences, Division of Biological Resources and Development, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.
Manabu NiimiDepartment of Molecular Pathology, Faculty of Medicine, Interdisciplinary Graduate School of Medical Sciences, University of Yamanashi, 1110 Shimokato, Chuo 409-3898, Japan.ORCID 0000-0002-3694-5642
Chen-Chi WangAnimal Resources Section, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa 904-0495, Japan.
Jianglin FanDepartment of Molecular Pathology, Faculty of Medicine, Interdisciplinary Graduate School of Medical Sciences, University of Yamanashi, 1110 Shimokato, Chuo 409-3898, Japan.ORCID 0000-0002-1737-6130
Saga University · JPNational Institutes of Natural Sciences · JPOkinawa Institute of Science and Technology Graduate University · JPUniversity of Yamanashi · JPWuyi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rabbit is a valuable animal for both the economy and biomedical sciences. Sperm cryopreservation is one of the most efficient ways to preserve rabbit strains because it is easy to collect ejaculate repeatedly from a single male and inseminate artificially into multiple females. During the cooling, freezing and thawing process of sperms, the plasma membrane, cytoplasm and genome structures could be damaged by osmotic stress, cold shock, intracellular ice crystal formation, and excessive production of reactive oxygen species. In this review, we will discuss the progress made during the past years regarding efforts to minimize the cell damage in rabbit sperms, including freezing extender, cryoprotectants, supplements, and procedures.

Indexed as

animal modelassisted reproductive technologycryopreservationrabbitsperm quality

Identifiers

PMID33922622
PMCPMC8145333
OpenAlexW3157910879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.