Evidence map›Paper›PMID 33922581›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Nanocomposite Membrane Scaffolds for Cell Function Maintaining for Biomedical Purposes.

Monika Drabik, Anna Grzeczkowicz, Paweł Bącal, Angelika Kwiatkowska, Marcin Strawski, Magdalena Antosiak-Iwańska, Beata Kazimierczak, Ewa Godlewska, Ludomira H Granicka

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Monika DrabikNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.ORCID 0000-0003-2889-5072
Anna GrzeczkowiczNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.ORCID 0000-0002-8970-4578
Paweł BącalNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Angelika KwiatkowskaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.ORCID 0000-0002-4088-3085
Marcin StrawskiLaboratory of Electrochemistry, Faculty of Chemistry, Warsaw University, 00-927 Warsaw, Poland.ORCID 0000-0002-8253-0878
Magdalena Antosiak-IwańskaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Beata KazimierczakNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Ewa GodlewskaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.
Ludomira H GranickaNalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, 01-224 Warsaw, Poland.ORCID 0000-0001-7890-0883
Institute of Biocybernetics and Biomedical Engineering · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanocomposite multilayered membrane coatings have been widely used experimentally to enhance biomedical materials surfaces. By the selection of reliable components, such systems are functionalized to be adjusted to specific purposes. As metal nanoparticles can reduce bacterial cell adhesion, the idea of using gold and silver nanoparticles of unique antimicrobial properties within membrane structure is outstandingly interesting considering dressings facilitating wound healing. The study was aimed to explore the interface between eukaryotic cells and wound dressing materials containing various nanoelements. The proposed systems are based on polyethyleneimine and hydroxyapatite thin layers incorporating metallic nanoparticles (silver or gold). To examine the structure of designed materials scanning electron and transmission electron microscopies were applied. Moreover, Fourier-transform infrared and energy-dispersive X-ray spectroscopies were used. Additionally, water contact angles of the designed membranes and their transport properties were estimated. The functioning of human fibroblasts was examined via flow cytometry to assess the biocompatibility of developed shells in the aspect of their cytotoxicity. The results indicated that designed nanocomposite membrane scaffolds support eukaryotic cells' functioning, confirming that the elaborated systems might be recommended as wound healing materials.

Indexed as

biological characterizationhuman fibroblastsmetal nanoparticlesnanocomposite membrane scaffoldsnanotechnologyregenerative medicinetransport

Identifiers

PMID33922581
PMCPMC8146798
OpenAlexW3158107387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.