ArticlePathogens (Basel, Switzerland)2021
Drift of the Subgingival Periodontal Microbiome during Chronic Periodontitis in Type 2 Diabetes Mellitus Patients.
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Molecular and Genomic Mechanisms Linking Diabetes Mellitus and Periodontitis: From Pathogenesis to Translational Opportunities.International journal of molecular sciences · 2026Review
- Comparative Analysis of Oral Microbiome in Indian Type 2 Diabetes Mellitus (T2DM) and Periodontitis Cohorts.Diseases (Basel, Switzerland) · 2026Article
- Comparison of 16S rRNA gene amplicon and whole-genome shotgun metagenomic sequencing for subgingival oral microbiome profiling.Journal of oral microbiology · 2026Article
- Severe periodontitis patients with well-controlled type 2 diabetes display a distinct subgingival microbiome with increased Saccharibacteria compared to systemically healthy controls.Frontiers in cellular and infection microbiology · 2026Article
- Signature of oral microbial dysbiosis in different periodontitis risk levels.Applied microbiology and biotechnology · 2025Article
- Photocatalytic TiORSC advances · 2025Article
- Salivary microbiome and periodontopathogen/denitrifying bacteria associated with gingivitis and periodontitis in people with type 2-diabetes.F1000Research · 2025Article
- Analysis of the diversity and function of the microbiota in infected root canals of type 2 diabetes mellitus with apical periodontitis.Frontiers in cellular and infection microbiology · 2025Article
- Salivary microbiome variations in type 2 diabetes mellitus patients with different stages of periodontitis.BMC oral health · 2024Article
- Alterations in subgingival microbiome and advanced glycation end-products levels in periodontitis with and without type 1 diabetes mellitus: a cross-sectional study.BMC oral health · 2024Article
- Relationship Between Diabetes Mellitus and Periodontal/Peri-Implant Disease: A Contemporaneous Review.International dental journal · 2024Review
- Microbiomic insights into the oral microbiome's role in type 2 diabetes mellitus: standardizing approaches for future advancements.Frontiers in endocrinology · 2024Review
- From-Toilet-to-Freezer: A Review on Requirements for an Automatic Protocol to Collect and Store Human Fecal Samples for Research Purposes.Biomedicines · 2023Review
- The Bidirectional Relationship between Periodontal Disease and Diabetes Mellitus-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Studying ancient human oral microbiomes could yield insights into the evolutionary history of noncommunicable diseases.F1000Research · 2023Review
- Diabetes mellitus promotes susceptibility to periodontitis-novel insight into the molecular mechanisms.Frontiers in endocrinology · 2023Review
- Biomarkers and Pathogenesis of Infectious and Autoimmune Diseases.Pathogens (Basel, Switzerland) · 2022Article
- Cross-Cohort Microbiome Analysis of Salivary Biomarkers in Patients With Type 2 Diabetes Mellitus.Frontiers in cellular and infection microbiology · 2022Article
- Analysis of subgingival micro-organisms based on multi-omics and Treg/Th17 balance in type 2 diabetes with/without periodontitis.Frontiers in microbiology · 2022Article
- Pyroptosis in periodontitis: From the intricate interaction with apoptosis, NETosis, and necroptosis to the therapeutic prospects.Frontiers in cellular and infection microbiology · 2022Review
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 1 country.
Funding
Abstract
Since periodontitis and type 2 diabetes mellitus are complex diseases, a thorough understanding of their pathogenesis requires knowing the relationship of these pathologies with other disorders and environmental factors. In this study, the representability of the subgingival periodontal microbiome of 46 subjects was studied by 16S rRNA gene sequencing and shotgun sequencing of pooled samples. We examined 15 patients with chronic periodontitis (CP), 15 patients with chronic periodontitis associated with type 2 diabetes mellitus (CPT2DM), and 16 healthy subjects (Control). The severity of generalized chronic periodontitis in both periodontitis groups of patients (CP and CPT2DM) was moderate (stage II). The male to female ratios were approximately equal in each group (22 males and 24 females); the average age of the subjects was 53.9 ± 7.3 and 54.3 ± 7.2 years, respectively. The presence of overweight patients (Body Mass Index (BMI) 30-34.9 kg/m
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Registered trials
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